Protein Alignment tpr and Cfd

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_038487.1
• Gene: Cfd / 11537
• MGIID: 87931
• Length: 259
• Species: Mus musculus
• Alignment Length: 249
• Identity: 78/249 - (31%)
• Similarity: 127/249 - (51%)
• Gaps: 19/249 - (7%)

  Fly   117 VCGIANIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRKERISVRL 181
            ||. |..:.||:||||...|..|::|.:...|...|..:||::|::|:|:||:.|...:. ||::
Mouse    17 VCA-AQPRGRILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDD-SVQV 79

  Fly   182 LEHDRKMSHMQKIDR--KVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPTPGRSFK 244
            |.....:|..:...|  .|..|:.||.....:.::|:.:.||.:.......:.|  :|......:
Mouse    80 LLGAHSLSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRP--LPLQYEDKE 142

  Fly   245 GENGI---VTGWGALKVGGPTSDTLQEVQVPILSQDECR-KSRYGNKITDNMLCGGYDEGGKDSC 305
            .|.|.   |.|||.:...|...|.|.:::|.|:::..|. ::.:...:|.||:|.  :...:|:|
Mouse   143 VEPGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCA--ESNRRDTC 205

  Fly   306 QGDSGGPLHIVASGTREHQIAGVVSWGEG-CAKAGYPGVYARVNRYGTWIKNLT 358
            :||||.||   ..|   ..:.|||:||.. |.....||||.||:.|..||:|:|
Mouse   206 RGDSGSPL---VCG---DAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENIT 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	72/235 (31%)
Cfd	NP_038487.1	Tryp_SPc	26..252	CDD:238113	72/236 (31%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		2/3 (67%)