Protein Alignment tpr and Acr

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_038483.1
• Gene: Acr / 11434
• MGIID: 87884
• Length: 436
• Species: Mus musculus
• Alignment Length: 307
• Identity: 99/307 - (32%)
• Similarity: 139/307 - (45%)
• Gaps: 50/307 - (16%)

  Fly    74 MMPDAASTTSTTTPAPSSSTTTTRRATTPAPPTLNPPRNCSDCVCGIANIQK-----RIVGGQET 133
            |:|..|......:.....:||                  | |..||:...|.     |||.||..
Mouse     4 MLPTVAVLVLAVSVVAKDNTT------------------C-DGPCGLRFRQNSQAGTRIVSGQSA 49

  Fly   134 EVHQYPWVAML----LYGGRFY--CAASLLNDQFLLTASHC------VYGFRKERISVRLLEHDR 186
            ::..:||:..|    .:..|.|  |..||||..::|||:||      ||.:|.. ...:.:|:.|
Mouse    50 QLGAWPWMVSLQIFTSHNSRRYHACGGSLLNSHWVLTAAHCFDNKKKVYDWRLV-FGAQEIEYGR 113

  Fly   187 -KMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPTPGRSFKG----- 245
             |.....:.:|.|.:::.|.|||.....||||::|:..||.....:.|.|:|    .||.
Mouse   114 NKPVKEPQQERYVQKIVIHEKYNVVTEGNDIALLKITPPVTCGNFIGPCCLP----HFKAGPPQI 174

  Fly   246 -ENGIVTGWGALKVGGP-TSDTLQEVQVPILSQDECRKSR-YGNKITDNMLCGGYDEGGKDSCQG 307
             ....|||||.:|...| .|..|.|.:|.::..|.|..:: |..::|...:|.||.||..|:|||
Mouse   175 PHTCYVTGWGYIKEKAPRPSPVLMEARVDLIDLDLCNSTQWYNGRVTSTNVCAGYPEGKIDTCQG 239

  Fly   308 DSGGPLHIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYGTWI 354
            ||||||....:......:.|:.|||.|||:|..||||.....|..||
Mouse   240 DSGGPLMCRDNVDSPFVVVGITSWGVGCARAKRPGVYTATWDYLDWI 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	88/249 (35%)
Acr	NP_038483.1	Tryp_SPc	42..286	CDD:214473	87/248 (35%)