Protein Alignment tpr and KLK8

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 84/269 - (31%)
• Similarity: 131/269 - (48%)
• Gaps: 40/269 - (14%)

  Fly   100 TTPAPPTLNPPRNCSDCVCGIANIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLT 164
            :.|.||.....|...|          :::||.|.:.|..||.|.|..|.:..|...|:...::||
Human    61 SNPLPPAAGHSRAQED----------KVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLT 115

  Fly   165 ASHCVYGFRKERISVRLLEHDRKMSHMQKIDRKVAEVITHPKYNA---RNYDNDIAIIKLDEPVE 226
            |:||    :|.:.:|||.:|..:.....:.:..|.:.|.||.||:   .::::|:.:::|.:...
Human   116 AAHC----KKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQAS 176

  Fly   227 FNEVLHPVCM----PTPGRSFKGENGIVTGWGALKVGGPTS---DTLQEVQVPILSQDECRKSRY 284
            ....:.|:.:    ..|     |:...|:|||.  |..|..   |||...:|.|..|.:| :..|
Human   177 LGSKVKPISLADHCTQP-----GQKCTVSGWGT--VTSPRENFPDTLNCAEVKIFPQKKC-EDAY 233

  Fly   285 GNKITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWG-EGCAKAGYPGVYARVN 348
            ..:|||.|:|.|..:|. |:|||||||||  |..|.    :.|:.||| :.|.::..||||..:.
Human   234 PGQITDGMVCAGSSKGA-DTCQGDSGGPL--VCDGA----LQGITSWGSDPCGRSDKPGVYTNIC 291

  Fly   349 RYGTWIKNL 357
            ||..|||.:
Human   292 RYLDWIKKI 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	78/239 (33%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	76/238 (32%)