Protein Alignment tpr and PRSS21

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 95/288 - (32%)
• Similarity: 139/288 - (48%)
• Gaps: 42/288 - (14%)

  Fly   103 APPTLNPPRNCSDCVCGIANIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASH 167
            |.|...|        ||...|..|||||::.|:.::||...|.......|..|||:.::.|||:|
Human    26 AAPLSGP--------CGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAH 82

  Fly   168 CVYGFRKERISVRLLEHDRKMSHMQKIDRK--------------VAEVITHPKYNARNYDNDIAI 218
            |...:..      |.:....|....::...              |:.:...|:| ..|...|||:
Human    83 CFETYSD------LSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRY-LGNSPYDIAL 140

  Fly   219 IKLDEPVEFNEVLHPVCMPTPGRSFKGENGI---VTGWGALKVGG--PTSDTLQEVQVPILSQDE 278
            :||..||.:.:.:.|:|:  ...:|:.||..   |||||.:|...  |:..|||||||.|::...
Human   141 VKLSAPVTYTKHIQPICL--QASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSM 203

  Fly   279 CR----KSRYGNKITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAG 339
            |.    |..:...|..:|:|.|..:||||:|.|||||||....:|. .:|| ||||||.||.:..
Human   204 CNHLFLKYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNGL-WYQI-GVVSWGVGCGRPN 266

  Fly   340 YPGVYARVNRYGTWIKNLTKQACLCQQE 367
            .||||..::.:..||:.|..|:.:.|.:
Human   267 RPGVYTNISHHFEWIQKLMAQSGMSQPD 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	85/251 (34%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	85/251 (34%)