DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tpr and tmprss2.14

DIOPT Version :9

Sequence 1:	NP_611611.1	Gene:	tpr / 37486	FlyBaseID:	FBgn0034661	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	XP_031752402.1	Gene:	tmprss2.14 / 101731505	XenbaseID:	XB-GENE-22065937	Length:	504	Species:	Xenopus tropicalis

Alignment Length:	246	Identity:	82/246 - (33%)
Similarity:	121/246 - (49%)	Gaps:	9/246 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 CV-CGIA-NIQKRIVGGQETEVHQYPWVAMLL--YGGRFY-CAASLLNDQFLLTASHCVYGFRKE 175
            |: ||:: .:..|||||.......:||...||  .|...| |..|::...:::||:|||||....
Frog   252 CISCGLSTKVDSRIVGGTVASAGDWPWQVQLLKRVGASLYLCGGSIITQHWVVTAAHCVYGSTST 316

  Fly   176 RISVRLLEHDRKMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPTPG 240
            ..:.::......:.........|...:.||.|::...:.|:|::||...:.|...|.|||:|..|
Frog   317 PSAFKVFAGSLTIQSYYSAGYTVERALVHPSYSSYTQNYDVALLKLTAALVFTTNLRPVCLPNVG 381

  Fly   241 RSF-KGENGIVTGWGALKVGGPTSDTLQEVQVPILSQDECRKSR-YGNKITDNMLCGGYDEGGKD 303
            ..: :|:...::|||....||..|..|:...||::|...|.::. ||..|:..|:|.||..||.|
Frog   382 MPWAEGQPCWISGWGTTSNGGSISTNLKAASVPLISSATCNQAAVYGGAISPTMMCAGYLSGGTD 446

  Fly   304 SCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYGTWI 354
            :|||||||||  |........:.|..|||.||.....||||..:.....||
Frog   447 TCQGDSGGPL--VTKTNSLWWLVGDTSWGYGCGMTNKPGVYGNLTFSLEWI 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	126..354	CDD:214473	77/232 (33%)
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	78/233 (33%)
tmprss2.14	XP_031752402.1	LDLa	<96..121	CDD:238060
		LDLa	128..159	CDD:238060
		SRCR_2	164..259	CDD:406055	3/6 (50%)
		Tryp_SPc	265..497	CDD:238113	78/233 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380103at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010