DRSC/TRiP Functional Genomics Resources

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Protein Alignment tpr and tmprss6

DIOPT Version :9

Sequence 1:NP_611611.1 Gene:tpr / 37486 FlyBaseID:FBgn0034661 Length:372 Species:Drosophila melanogaster
Sequence 2:XP_004913946.2 Gene:tmprss6 / 100489045 XenbaseID:XB-GENE-1011573 Length:806 Species:Xenopus tropicalis


Alignment Length:266 Identity:100/266 - (37%)
Similarity:148/266 - (55%) Gaps:29/266 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly   112 NCSD------CVCGIANIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVY 170
            :|.|      |.|||..:..|:|||.:.:..::||.|.|...|...|..:|:.||::|||:||  
 Frog   550 DCPDGSDENNCGCGIQAVGIRLVGGTQAQEGEWPWQASLQVRGEHICGGTLVADQWILTAAHC-- 612

  Fly   171 GFRKERIS-----------VRLLEHDRKMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEP 224
             |..|..:           |||     ..|..:::..||..::.||.|:..::|.|:|::.||..
 Frog   613 -FTPESYASPEVWTVYLGKVRL-----SRSTQKELAFKVIRLVIHPFYDEDSHDYDVALVLLDHL 671

  Fly   225 VEFNEV-LHPVCMPTPGRSF-KGENGIVTGWGALKVGGPTSDTLQEVQVPILSQDECRKSRYGNK 287
            |..... :.|:|:|:....| .|.:..|||||::|..|||||.||:|.:.:::||.|.: .|..:
 Frog   672 VPLTSPHVQPICLPSSTHHFPTGSSCWVTGWGSVKENGPTSDVLQKVDIQLVAQDICTE-LYRYQ 735

  Fly   288 ITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYGT 352
            |:..|||.||.:|.||:||||||.||....:..|..| ||:||||.||....|.|||:|:.|...
 Frog   736 ISPRMLCAGYRDGSKDACQGDSGSPLVCKTASGRWFQ-AGLVSWGAGCGIPRYFGVYSRITRLVQ 799

  Fly   353 WIKNLT 358
            ||:::|
 Frog   800 WIESIT 805

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tprNP_611611.1 Tryp_SPc 126..354 CDD:214473 91/240 (38%)
Tryp_SPc 127..356 CDD:238113 92/241 (38%)
tmprss6XP_004913946.2 SEA 77..176 CDD:396113
CUB 235..303 CDD:412131
LDLa 448..478 CDD:238060
LDLa 480..514 CDD:238060
LDLa 525..560 CDD:238060 2/9 (22%)
Tryp_SPc 572..804 CDD:238113 92/241 (38%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R8078
SonicParanoid 1 1.000 - - X11
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.940

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