Protein Alignment tpr and tmprss6

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: XP_004913946.2
• Gene: tmprss6 / 100489045
• XenbaseID: XB-GENE-1011573
• Length: 806
• Species: Xenopus tropicalis
• Alignment Length: 266
• Identity: 100/266 - (37%)
• Similarity: 148/266 - (55%)
• Gaps: 29/266 - (10%)

  Fly   112 NCSD------CVCGIANIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVY 170
            :|.|      |.|||..:..|:|||.:.:..::||.|.|...|...|..:|:.||::|||:||
 Frog   550 DCPDGSDENNCGCGIQAVGIRLVGGTQAQEGEWPWQASLQVRGEHICGGTLVADQWILTAAHC-- 612

  Fly   171 GFRKERIS-----------VRLLEHDRKMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEP 224
             |..|..:           |||     ..|..:::..||..::.||.|:..::|.|:|::.||..
 Frog   613 -FTPESYASPEVWTVYLGKVRL-----SRSTQKELAFKVIRLVIHPFYDEDSHDYDVALVLLDHL 671

  Fly   225 VEFNEV-LHPVCMPTPGRSF-KGENGIVTGWGALKVGGPTSDTLQEVQVPILSQDECRKSRYGNK 287
            |..... :.|:|:|:....| .|.:..|||||::|..|||||.||:|.:.:::||.|.: .|..:
 Frog   672 VPLTSPHVQPICLPSSTHHFPTGSSCWVTGWGSVKENGPTSDVLQKVDIQLVAQDICTE-LYRYQ 735

  Fly   288 ITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYGT 352
            |:..|||.||.:|.||:||||||.||....:..|..| ||:||||.||....|.|||:|:.|...
 Frog   736 ISPRMLCAGYRDGSKDACQGDSGSPLVCKTASGRWFQ-AGLVSWGAGCGIPRYFGVYSRITRLVQ 799

  Fly   353 WIKNLT 358
            ||:::|
 Frog   800 WIESIT 805

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	92/241 (38%)
tmprss6	XP_004913946.2	SEA	77..174	CDD:460188
		CUB	235..303	CDD:412131
		LDLa	448..478	CDD:238060
		LDLa	480..514	CDD:238060
		LDLa	525..560	CDD:238060	2/9 (22%)
		Tryp_SPc	572..804	CDD:238113	92/241 (38%)