DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Loxl2 and Scara5

DIOPT Version :9

Sequence 1:	NP_523806.2	Gene:	Loxl2 / 37485	FlyBaseID:	FBgn0034660	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_083179.2	Gene:	Scara5 / 71145	MGIID:	1918395	Length:	491	Species:	Mus musculus

Alignment Length:	103	Identity:	46/103 - (44%)
Similarity:	60/103 - (58%)	Gaps:	0/103 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 IRLVGGDNEYEGNIEVLHNGKWGAVCDDEWDSTEADIVCRQLGFPGMRRYTRSGFFGPARRRFWM 125
            ||||.|...::|.:||.|:.:||.||||.||..:.|:|||.|||.|:....|:..||....|.||
Mouse   389 IRLVNGSGPHQGRVEVFHDRRWGTVCDDGWDKKDGDVVCRMLGFHGVEEVYRTARFGQGTGRIWM 453

  Fly   126 DNLFCEGHEQELVDCHFEGWGENDCEPGEAAGVVCYPP 163
            |::.|:|.|..:..|.|..||..:|...|.|||.|..|
Mouse   454 DDVNCKGTESSIFHCQFSKWGVTNCGHAEDAGVTCTVP 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Loxl2	NP_523806.2	SR	61..161	CDD:214555	44/99 (44%)
		SRCR	66..160	CDD:278931	40/93 (43%)
		SR	193..298	CDD:214555
		SRCR	198..298	CDD:278931
		Lysyl_oxidase	303..503	CDD:279521
Scara5	NP_083179.2	PRK09039	55..>249	CDD:181619
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	301..380
		Collagen	318..373	CDD:396114
		SR	389..489	CDD:214555	44/99 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	104	1.000	Domainoid score	I6740
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000