Protein Alignment Loxl2 and SCART1

DIOPT Version :10

• Sequence 1: NP_523806.2
• Gene: Loxl2 / 37485
• FlyBaseID: FBgn0034660
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001382979.1
• Gene: SCART1 / 619207
• HGNCID: 32411
• Length: 1027
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 92/298 - (30%)
• Similarity: 111/298 - (37%)
• Gaps: 104/298 - (34%)

  Fly    77 LHNGKWGAVCDDEWDSTEADIVCRQLGFPGMRRYTRSGFFGPARRRFWMDNLFCEGHEQELVDCH 141
            ||.|.||.||||.||..:|.:||||||.........:..||....|.|:|.|.|:|||..|..|.
Human   572 LHGGAWGTVCDDAWDLRDAHVVCRQLGCGRALSALGAAHFGAGAGRIWLDELGCQGHESALWQCP 636

  Fly   142 FEGWGENDCEPGEAAGVVCYP-------------------------------------------- 162
            ..|||.:|....|.|||.|..
Human   637 SAGWGRHDWRHKEDAGVFCSESVALRLRGGTCCCAGWLDVFYNGTWGAMCSNALKDLSLSIICKQ 701

  Fly   163 -------------------------------PENALI--------PMATPIIR------DEDLPK 182
                                           |:.|.:        |||..::|      .||.|:
Human   702 LGCGVWGVGLAGEQALPLCGHRDRLGGQHRVPQAAQLHSVAMPFPPMAPALLRPSRAGLSEDRPQ 766

  Fly   183 ---YPIHSRSRL------YVRLRGGRSRIEGRVEVSLDGGRWGSVCADGWSLLEANVVCRQLGLG 238
               .|::..|.|      .:|:|||..|..||||: ...|.||:||.|||.|.:|.|||||||.|
Human   767 AAGEPLNCSSWLGCPEEGALRVRGGEDRCSGRVEL-WHAGSWGTVCDDGWDLADAEVVCRQLGCG 830

  Fly   239 YASEAFQTDFFG-GFNVSRPV-LSGSECYGNETELADC 274
            .|..|.....|| |   |.|| |....|.|:|..|..|
Human   831 RAVAALGAAAFGPG---SGPVWLDEVGCRGSEASLWGC 865

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Loxl2	NP_523806.2	SR	61..161	CDD:214555	38/83 (46%)
		SR	193..298	CDD:214555	41/84 (49%)
		Lysyl_oxidase	303..506	CDD:460102
SCART1	NP_001382979.1	SR	28..128	CDD:214555
		SR	233..326	CDD:214555
		SR	329..428	CDD:214555
		SRCR	439..534	CDD:459844
		SR	<579..656	CDD:214555	33/76 (43%)
		SR	661..>705	CDD:214555	0/43 (0%)
		SR	786..885	CDD:214555	41/84 (49%)