DRSC/TRiP Functional Genomics Resources

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Protein Alignment Loxl2 and Cd5

DIOPT Version :9

Sequence 1:NP_523806.2 Gene:Loxl2 / 37485 FlyBaseID:FBgn0034660 Length:511 Species:Drosophila melanogaster
Sequence 2:NP_062168.2 Gene:Cd5 / 54236 RGDID:2309 Length:503 Species:Rattus norvegicus


Alignment Length:451 Identity:94/451 - (20%)
Similarity:153/451 - (33%) Gaps:153/451 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    61 IRLVGGDNEYEGNIEVLHNGKWGAVCDDEW--------DSTEADIVCRQLGFPGMRRYTRSGFFG 117
            :.|.|.:::.:|.:||..|| ...||...|        ::.||..||:|||.        .....
  Rat    46 VMLSGSNSKCQGLVEVQMNG-MKTVCSSSWRLSQDLWKNANEASTVCQQLGC--------GNPLA 101

  Fly   118 PARRRFW---MDNLFCEGHEQELVDCHFEGWGENDCEPGEAAGVVCYPPENALIPMATPIIRDED 179
            ......|   .:.:.|:|......:|.....|:  |.|   ..:||..|:.. .|:.|..: ...
  Rat   102 LGHLTLWNRPKNQILCQGPPWSFSNCSTSSLGQ--CLP---LSLVCLEPQKT-TPLPTTTL-PTT 159

  Fly   180 LPKYPIHSRSRLYVRLRGGRSRIEGRVEVSLDGGRWGSVCADGWSLLEA--------NVVCRQLG 236
            :|:.....|.:|.....|  .|..|.||. .:|.|.|::      |.:|        |::|:.|.
  Rat   160 MPEPTAPPRLQLVPGHEG--LRCTGVVEF-YNGSRGGTI------LYKAKARPVDLGNLICKSLQ 215

  Fly   237 LGYASEAFQTDFFGGFNVSRPVLSGSECYGNETELAD----CLHHDASQGIISCHGNRQHVAAVI 297
            .|    :|.|      ::||...:|:..   ..||.|    .:..:|..|  ||...:|      
  Rat   216 CG----SFLT------HLSRIETAGTPA---PAELRDPRPLPIRWEAQNG--SCTSLQQ------ 259

  Fly   298 CDYIAPDLVVDYLEIEQTAHLEDRPMLLMQCAMEENCVANEAYQIQRDDPHWRYRSRRLLKFTAA 362
            |             .::|...|....|.:.|:                |...:.:||.:   ..:
  Rat   260 C-------------FQKTTVQEGSQALAVVCS----------------DFQPKVQSRLV---GGS 292

  Fly   363 AINAGNADFRPFKEKSQW-------------EW-HMCH-------MHFHSMEVFATFDIFNLRGI 406
            ::..|.|:.|   ::|||             .| .:|.       :.||.|:...|..     |:
  Rat   293 SVCEGIAEVR---QRSQWAALCDSSAARGPGRWEELCQEQQCGNLISFHVMDADRTSP-----GV 349

  Fly   407 KVAQGHKASFCLEDSNCLPGVAKKYNCANYGDQGISINCSDVYLYNLDCQWVDVTDLIPGT 467
            ...| .|.|.|.:       :.||.:|     :.:.|.|.|          .:...|.|||
  Rat   350 LCTQ-EKLSQCYQ-------LQKKTHC-----KRVFITCKD----------PNPVGLAPGT 387

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Loxl2NP_523806.2 SR 61..161 CDD:214555 25/110 (23%)
SRCR 66..160 CDD:278931 22/104 (21%)
SR 193..298 CDD:214555 27/116 (23%)
SRCR 198..298 CDD:278931 26/111 (23%)
Lysyl_oxidase 303..503 CDD:279521 34/186 (18%)
Cd5NP_062168.2 SR 46..143 CDD:214555 25/110 (23%)
SR 287..368 CDD:214555 20/99 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166350592
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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