Protein Alignment Loxl2 and LOXL1

DIOPT Version :9

• Sequence 1: NP_523806.2
• Gene: Loxl2 / 37485
• FlyBaseID: FBgn0034660
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_005567.2
• Gene: LOXL1 / 4016
• HGNCID: 6665
• Length: 574
• Species: Homo sapiens
• Alignment Length: 207
• Identity: 86/207 - (41%)
• Similarity: 129/207 - (62%)
• Gaps: 6/207 - (2%)

  Fly   303 PDLVVDYLEIEQTAHLEDRPMLLMQCAMEENCVANEAYQIQRDDPHWRYRSRRLLKFTAAAINAG 367
            ||||.|...::.:.:::...:..::||.||.|:|:.||..:..|    |..|.||:|.....|.|
Human   370 PDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATD----YDVRVLLRFPQRVKNQG 430

  Fly   368 NADFRPFKEKSQWEWHMCHMHFHSMEVFATFDIFN-LRGIKVAQGHKASFCLEDSNCLPGVAKKY 431
            .|||.|.:.:..||||.||.|:|||:.|:.:|:.: ..|.|||:|||||||||||.|..|..|:|
Human   431 TADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASFCLEDSTCDFGNLKRY 495

  Fly   432 NCANYGDQGISINCSDVYLYNLDCQWVDVTDLIPGTYVLKIAINPEFKVAEMNYDNNAAICDLIY 496
            .|.:: .||:|..|.|.|..::||||:|:||:.||.|:||:.:||::.|.|.::.||...|::.|
Human   496 ACTSH-TQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHY 559

  Fly   497 TANFARVQNCQL 508
            |..:....||::
Human   560 TGRYVSATNCKI 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Loxl2	NP_523806.2	SR	61..161	CDD:214555
		SRCR	66..160	CDD:278931
		SR	193..298	CDD:214555
		SRCR	198..298	CDD:278931
		Lysyl_oxidase	303..503	CDD:279521	84/200 (42%)
LOXL1	NP_005567.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	62..123
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	239..374		3/3 (100%)
		Lysyl-oxidase like	370..574		86/207 (42%)
		Lysyl_oxidase	370..566	CDD:279521	84/200 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D376277at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45817
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.020