DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Loxl2 and LGALS3BP

DIOPT Version :9

Sequence 1:	NP_523806.2	Gene:	Loxl2 / 37485	FlyBaseID:	FBgn0034660	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_005558.1	Gene:	LGALS3BP / 3959	HGNCID:	6564	Length:	585	Species:	Homo sapiens

Alignment Length:	103	Identity:	39/103 - (37%)
Similarity:	55/103 - (53%)	Gaps:	0/103 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 EGAIRLVGGDNEYEGNIEVLHNGKWGAVCDDEWDSTEADIVCRQLGFPGMRRYTRSGFFGPARRR 122
            :|.:||..|....:|.:|:.:.|:||.|||:.||.|:|.:|||.|||....:......||.....
Human    21 DGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGSGP 85

  Fly   123 FWMDNLFCEGHEQELVDCHFEGWGENDCEPGEAAGVVC 160
            ..:|.:.|.|.|..|.||...||.:::|.....|||||
Human    86 IMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVC 123

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Loxl2	NP_523806.2	SR	61..161	CDD:214555	38/100 (38%)
		SRCR	66..160	CDD:278931	34/93 (37%)
		SR	193..298	CDD:214555
		SRCR	198..298	CDD:278931
		Lysyl_oxidase	303..503	CDD:279521
LGALS3BP	NP_005558.1	SR	24..124	CDD:214555	38/100 (38%)
		BTB_POZ_M2BP	136..247	CDD:349613
		BACK_LGALS3BP	256..329	CDD:350571
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156679
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930