Protein Alignment Loxl2 and Loxl2

DIOPT Version :10

• Sequence 1: NP_523806.2
• Gene: Loxl2 / 37485
• FlyBaseID: FBgn0034660
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: XP_038949076.1
• Gene: Loxl2 / 290350
• RGDID: 1308435
• Length: 823
• Species: Rattus norvegicus
• Alignment Length: 507
• Identity: 198/507 - (39%)
• Similarity: 273/507 - (53%)
• Gaps: 83/507 - (16%)

  Fly    49 RYTKVLNKEEG-------AIRLVGGDNEYEGNIEVLHNGKWGAVCDDEWDSTEADIVCRQLGF-- 104
            |:.|....|:.       .:||.||....||.:|||.||:||.||||:||...|.:|||:|||
  Rat   329 RFRKAYKPEQDHVSLQQPLVRLRGGAQVGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGT 393

  Fly   105 -----PGMR-------RYTR--------------SGF----FGPARRRFWMDNLFCEGHEQELVD 139
                 .|.|       .||.              ||.    .||..    ::.:.|.|.|:.::|
  Rat   394 AKEAVTGSRLGQGIGWEYTEGKHGIPALLLGKASSGSECTGIGPIH----LNEVQCTGTEKSIID 454

  Fly   140 C--HFEGWGENDCEPGEAAGVVCYPPENALIPMATPIIRDEDLPKYPIHSRSRLYVRLRGGRSRI 202
            |  :.|..|   |...|.|||.|                  ::|......:    |||.|||:..
  Rat   455 CKLNTESQG---CNHEEDAGVRC------------------NIPIMGFQKK----VRLNGGRNPY 494

  Fly   203 EGRVEVSLDGGR---WGSVCADGWSLLEANVVCRQLGLGYASEAFQTDFF--GGFNVSRPVLSGS 262
            ||||||..:...   ||:||...|.::||.|||||||||:||.|||..::  |....::.::||.
  Rat   495 EGRVEVLTERNGSLVWGNVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGNIFANKVIMSGV 559

  Fly   263 ECYGNETELADCLHHDASQGIISCHGNRQHVAAVICDYIAPDLVVDYLEIEQTAHLEDRPMLLMQ 327
            :|.|.|..||.|.|   .:.::...|..|:.|.|.|...|||||::...::|||:||||||.|:|
  Rat   560 KCSGTELSLAHCRH---DEEVVCPEGGVQYGAGVACSETAPDLVLNAEIVQQTAYLEDRPMALLQ 621

  Fly   328 CAMEENCVANEAYQIQRDDPHWRYRSRRLLKFTAAAINAGNADFRPFKEKSQWEWHMCHMHFHSM 392
            |||||||::..|........|     ||||:|::...|.|.:||||...:..|.||.||.|:|||
  Rat   622 CAMEENCLSASAVHTDPTRGH-----RRLLRFSSQIHNNGQSDFRPKNGRHAWIWHDCHRHYHSM 681

  Fly   393 EVFATFDIFNLRGIKVAQGHKASFCLEDSNCLPGVAKKYNCANYGDQGISINCSDVYLYNLDCQW 457
            |||..:|:.:|.|.|||:||||||||||:.|...:.|.|.|||:|:|||::.|.|:|.:::||||
  Rat   682 EVFTYYDLLSLNGTKVAEGHKASFCLEDTECEGDIQKSYECANFGEQGITMGCWDMYRHDIDCQW 746

  Fly   458 VDVTDLIPGTYVLKIAINPEFKVAEMNYDNNAAICDLIYTANFARVQNCQLG 509
            :|:||:.||.|:.::.|||.::|.|.::.||...|...|......:.||.:|
  Rat   747 IDITDVPPGDYLFQVVINPNYEVPESDFSNNIMKCRSRYDGYRIWMYNCHVG 798

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Loxl2	NP_523806.2	SR	61..161	CDD:214555	46/133 (35%)
		SR	193..298	CDD:214555	47/109 (43%)
		Lysyl_oxidase	303..506	CDD:460102	95/202 (47%)
Loxl2	XP_038949076.1	SR	73..174	CDD:214555
		SR	216..316	CDD:214555
		SR	348..475	CDD:214555	45/160 (28%)
		SR	485..593	CDD:214555	45/112 (40%)
		Lysyl_oxidase	597..795	CDD:460102	91/193 (47%)