Protein Alignment Loxl2 and DMBT1

DIOPT Version :10

• Sequence 1: NP_523806.2
• Gene: Loxl2 / 37485
• FlyBaseID: FBgn0034660
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001364459.1
• Gene: DMBT1 / 1755
• HGNCID: 2926
• Length: 2542
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 100/248 - (40%)
• Similarity: 131/248 - (52%)
• Gaps: 16/248 - (6%)

  Fly    60 AIRLVGGDNEYEGNIEVLHNGKWGAVCDDEWDSTEADIVCRQLGFPGMRRYTRSGFFGPARRRFW 124
            |:|||.||...:|.:|:|:.|.||.||||.||:.:|::||||||.........:.:||.......
Human   101 ALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIA 165

  Fly   125 MDNLFCEGHEQELVDCHFEGWGENDCEPGEAAGVVC--YPPENALIPMATPIIRDEDLPKYPIH- 186
            :|::.|.|||..|..|...||..::|..||.|||:|  ..|::.|.|.:.|:   ...|..|..
Human   166 LDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPV---RISPPVPTEG 227

  Fly   187 SRSRLYVRLRGGRSRIEGRVEVSLDGGRWGSVCADGWSLLEANVVCRQLGLGYASEAFQTDFFGG 251
            |.|.|.:||..|..|..||||| |..|.||:||.|.|...:|||||||||.|:|..|.....||
Human   228 SESSLALRLVNGGDRCRGRVEV-LYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFG- 290

  Fly   252 FNVSRP-VLSGSECYGNETELADCLHHDASQGIISCHGNRQHVAAVICDYIAP 303
             ..|.| ||....|.|:|:.|..|.|:    |.::.:......|.|||.  ||
Human   291 -QGSGPIVLDDVRCSGHESYLWSCPHN----GWLTHNCGHSEDAGVICS--AP 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Loxl2	NP_523806.2	SR	61..161	CDD:214555	42/101 (42%)
		SR	193..298	CDD:214555	44/105 (42%)
		Lysyl_oxidase	303..506	CDD:460102	1/1 (100%)
DMBT1	NP_001364459.1	SR	102..202	CDD:214555	41/99 (41%)
		SR	234..334	CDD:214555	45/106 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	335..356		2/2 (100%)
		SR	363..463	CDD:214555
		SR	494..594	CDD:214555
		SR	602..702	CDD:214555
		SR	733..833	CDD:214555
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	836..855
		SR	862..962	CDD:214555
		SR	993..1093	CDD:214555
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1093..1114
		SR	1122..1222	CDD:214555
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1222..1243
		SR	1251..1351	CDD:214555
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1351..1372
		SR	1380..1480	CDD:214555
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1480..1501
		SR	1509..1609	CDD:214555
		SR	1638..1738	CDD:214555
		SR	1769..1869	CDD:214555
		CUB	1904..2003	CDD:214483
		SR	2012..2115	CDD:214555
		CUB	2137..2245	CDD:238001
		ZP	2256..2508	CDD:214579