DRSC/TRiP Functional Genomics Resources

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Protein Alignment Loxl2 and Dmbt1

DIOPT Version :9

Sequence 1:NP_523806.2 Gene:Loxl2 / 37485 FlyBaseID:FBgn0034660 Length:511 Species:Drosophila melanogaster
Sequence 2:XP_006507361.2 Gene:Dmbt1 / 12945 MGIID:106210 Length:2061 Species:Mus musculus


Alignment Length:287 Identity:104/287 - (36%)
Similarity:137/287 - (47%) Gaps:31/287 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    38 DARQERQRLVHRYTKVLNKEEGAIRLVGGDNEYEGNIEVLHNGKWGAVCDDEWDSTEADIVCRQL 102
            |.....|..|..||.:..:...|:||..|.:..:|.:|:|:.|.||.||||.||..:|::|||||
Mouse   694 DQTTAEQTTVPDYTTIGTENSLAVRLENGGDRCQGRVEILYQGSWGTVCDDSWDLNDANVVCRQL 758

  Fly   103 G------FPGMRRYTRSGFFGPARRRFWMDNLFCEGHEQELVDCHFEGWGENDCEPGEAAGVVC- 160
            |      .||..|      ||.......||::.|.|:|..|..|...||..::|...|.|||:| 
Mouse   759 GCGLAVSAPGSAR------FGQGTGPIVMDDVACGGYEDYLWRCSHRGWLSHNCGHHEDAGVICS 817

  Fly   161 -----YPPENALIPMATPIIRDEDLPKY-PIHSRSRLYVRLRGGRSRIEGRVEVSLDGGRWGSVC 219
                 .|..:...|.....:....:|.| ||.:.:.|.|||..|..|.:||||: |..|.||:||
Mouse   818 ASQSSSPTPDVFYPTDQTTVEQTTVPDYTPIGTENSLAVRLENGGDRCQGRVEI-LYQGSWGTVC 881

  Fly   220 ADGWSLLEANVVCRQLGLGYASEAFQTDFFGGFNVSRPVLSGSECYGNETELADCLHHDASQGII 284
            .|.|...:|||||||||.|:|..|....:||..:.| .||....|.|:|..|..|.|    :|.:
Mouse   882 DDSWDTKDANVVCRQLGCGWAVSAPGNAYFGPGSGS-IVLDDVACTGHEDYLWSCSH----RGWL 941

  Fly   285 SCHGNRQHVAAVIC------DYIAPDL 305
            |.:......|.|||      ....|||
Mouse   942 SHNCGHHEDAGVICSDAQIQSTTRPDL 968

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Loxl2NP_523806.2 SR 61..161 CDD:214555 42/111 (38%)
SRCR 66..160 CDD:278931 39/99 (39%)
SR 193..298 CDD:214555 44/104 (42%)
SRCR 198..298 CDD:278931 41/99 (41%)
Lysyl_oxidase 303..503 CDD:279521 3/3 (100%)
Dmbt1XP_006507361.2 SR 33..133 CDD:214555
SR 152..252 CDD:214555
SR 301..401 CDD:214555
SR 439..539 CDD:214555
SR 578..678 CDD:214555
SR 717..817 CDD:214555 41/105 (39%)
SR 856..956 CDD:214555 45/105 (43%)
CUB 999..1107 CDD:238001
CUB 1115..1223 CDD:238001
CUB 1241..1349 CDD:238001
CUB 1357..1465 CDD:238001
SR 1486..1585 CDD:214555
CUB 1609..1717 CDD:238001
ZP 1728..1975 CDD:214579
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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