DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Loxl2 and LOC101733498

DIOPT Version :9

Sequence 1:	NP_523806.2	Gene:	Loxl2 / 37485	FlyBaseID:	FBgn0034660	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_031761233.1	Gene:	LOC101733498 / 101733498	-ID:	-	Length:	900	Species:	Xenopus tropicalis

Alignment Length:	259	Identity:	101/259 - (38%)
Similarity:	131/259 - (50%)	Gaps:	23/259 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 EEGAIRLVGGDNEYEGNIEVLHNGKWGAVCDDEWDSTEADIVCRQLGFPGMRRYTRSGFFGPARR 121
            |.|:||||.|....||.:|:.:||.||.||||.|:...|.:|||||.....:......|||..:.
Frog   407 EPGSIRLVNGGGRCEGRVEIYYNGTWGTVCDDLWNMNNARVVCRQLHCGEPKDAKIKAFFGSGKE 471

  Fly   122 RFWMDNLFCEGHEQELVDCHFEGWGENDCEPGEAAGVVC-------YPPENA------LIPMA-T 172
            |.||||:.|:|.|..|.||:|.|||.:||...|.|.|||       |..:.|      ::|.: |
Frog   472 RIWMDNVECDGSENALNDCNFPGWGLHDCSHNEDAAVVCSDQAASVYNEDTAKTTSKPVLPASGT 536

  Fly   173 PIIRDEDLPKYPIHSRSRL---YVRLRGGRSRIEGRVEVSLDGGRWGSVCADGWSLLEANVVCRQ 234
            |.......|:.|.||....   .:||..|..|.|||||:..: |.||:||.|.|::..|.|||||
Frog   537 PDKSHHLSPESPQHSPVATEPGSIRLVNGGGRCEGRVEIYYN-GTWGTVCDDLWNMSSARVVCRQ 600

  Fly   235 LGLGYASEAFQTDFFGGFNVSRPVLSGSECYGNETELADCLHHDASQGIISCHGNRQHVAAVIC 298
            |..|...:|.:..|||....| ..:...||.|:|..|.||  :....|:..|..|..  |.|:|
Frog   601 LHCGEPKDAKKDAFFGSGEES-IWMDNVECDGSENALNDC--NFRGWGLHDCSHNED--AGVVC 659

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Loxl2	NP_523806.2	SR	61..161	CDD:214555	48/106 (45%)
		SRCR	66..160	CDD:278931	42/93 (45%)
		SR	193..298	CDD:214555	41/104 (39%)
		SRCR	198..298	CDD:278931	39/99 (39%)
		Lysyl_oxidase	303..503	CDD:279521
LOC101733498	XP_031761233.1	SR	23..123	CDD:214555
		SR	176..276	CDD:214555
		SR	411..511	CDD:214555	47/99 (47%)
		SR	560..660	CDD:214555	42/106 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000389
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000