DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Loxl2 and loxl1

DIOPT Version :9

Sequence 1:	NP_523806.2	Gene:	Loxl2 / 37485	FlyBaseID:	FBgn0034660	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001096301.1	Gene:	loxl1 / 100124878	XenbaseID:	XB-GENE-1002050	Length:	525	Species:	Xenopus tropicalis

Alignment Length:	207	Identity:	85/207 - (41%)
Similarity:	131/207 - (63%)	Gaps:	6/207 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   303 PDLVVDYLEIEQTAHLEDRPMLLMQCAMEENCVANEAYQIQRDDPHWRYRSRRLLKFTAAAINAG 367
            ||||.|...::...:::...:..::||.||:|:::.||..:..|    |..|.||:|.....|.|
Frog   321 PDLVPDPSYVQAATYIQRAHLYSLKCAAEEHCLSSSAYSAEATD----YDVRVLLRFPQRVKNQG 381

  Fly   368 NADFRPFKEKSQWEWHMCHMHFHSMEVFATFDIFN-LRGIKVAQGHKASFCLEDSNCLPGVAKKY 431
            .|||.|.:.:..||||.||.|:|||:.|:.:|:.: ..|.|||:||||||||||:.|..|..|:|
Frog   382 TADFLPTRPRQSWEWHSCHQHYHSMDEFSHYDLLDATTGRKVAEGHKASFCLEDTTCDFGNLKRY 446

  Fly   432 NCANYGDQGISINCSDVYLYNLDCQWVDVTDLIPGTYVLKIAINPEFKVAEMNYDNNAAICDLIY 496
            .|.:: .||:|..|.|.|..::||||:|:|::.||.|:||:.:||::||.|.::.||...|::.|
Frog   447 ACTSH-TQGLSPGCYDTYNADIDCQWIDITEVKPGNYILKVVVNPKYKVLESDFTNNVVRCNIHY 510

  Fly   497 TANFARVQNCQL 508
            |..:|...||::
Frog   511 TGRYASATNCRI 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Loxl2	NP_523806.2	SR	61..161	CDD:214555
		SRCR	66..160	CDD:278931
		SR	193..298	CDD:214555
		SRCR	198..298	CDD:278931
		Lysyl_oxidase	303..503	CDD:279521	83/200 (42%)
loxl1	NP_001096301.1	Lysyl_oxidase	321..521	CDD:307371	84/204 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D376277at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45817
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020