DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4021 and FUBP1

DIOPT Version :9

Sequence 1:	NP_611610.2	Gene:	CG4021 / 37484	FlyBaseID:	FBgn0034659	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	XP_011540693.1	Gene:	FUBP1 / 8880	HGNCID:	4004	Length:	688	Species:	Homo sapiens

Alignment Length:	370	Identity:	65/370 - (17%)
Similarity:	110/370 - (29%)	Gaps:	164/370 - (44%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 DRVYATGR-IPGKELYADVYRQKPMKIIQKVFVPVNQYPKFNFAGKILGPKGNSLRRLQEETQCK 122
            |::...|| .||..     :...|...:|::.:|.::      ||.::|..|.::::|||....|
Human   186 DQIVEKGRPAPGFH-----HGDGPGNAVQEIMIPASK------AGLVIGKGGETIKQLQERAGVK 239

  Fly   123 IALKGRSSMRDRNKEEELR--SDPRYAHLQKNLFLEV-----------------------STVAI 162
            :.:. :...::...::.||  .||......|.:.||:                       ..|.|
Human   240 MVMI-QDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPI 303

  Fly   163 PAECHSRIAYAL---------------AEIRKYLIPDNNDEVSHEQLRELMEIDPESAKNFKGLN 212
            |     |.|..:               |.:|....||  |..:.|::.::.. .|:..::...:.
Human   304 P-----RFAVGIVIGRNGEMIKKIQNDAGVRIQFKPD--DGTTPERIAQITG-PPDRCQHAAEII 360

  Fly   213 LEAYRSVRDSN-----------------------GASKYINL-----------------IKRVAE 237
            .:..|||:..|                       |..:..|.                 ||.:::
Human   361 TDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQ 425

  Fly   238 ----------NPSKVAD-----------MEQVDY--------------------DYDEHHMPPIH 261
                      ||...||           .:|:||                    .:..|.:|..|
Human   426 QSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPH 490

  Fly   262 LPTGYEYSIQRPSKIVAKFKRPYPYP-TDMKPVREPPIKFYKPNP 305
            .|.|                 | |.| |.|.|....|   |.|.|
Human   491 GPPG-----------------P-PGPGTPMGPYNPAP---YNPGP 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4021	NP_611610.2	SF1_like-KH	86..202	CDD:239088	28/155 (18%)
FUBP1	XP_011540693.1	KH-I	119..193	CDD:412160	1/6 (17%)
		KH-I	207..276	CDD:412160	17/75 (23%)
		KH-I	297..364	CDD:412160	12/74 (16%)
		KH-I	397..468	CDD:412160	10/70 (14%)
		DUF1897	623..>643	CDD:401086
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D590738at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010