DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4021 and khdrbs2

DIOPT Version :9

Sequence 1:	NP_611610.2	Gene:	CG4021 / 37484	FlyBaseID:	FBgn0034659	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_001072215.1	Gene:	khdrbs2 / 779662	XenbaseID:	XB-GENE-490722	Length:	345	Species:	Xenopus tropicalis

Alignment Length:	220	Identity:	85/220 - (38%)
Similarity:	126/220 - (57%)	Gaps:	28/220 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 QKFLADLDEERQRLSAEFPLCALLIDE--ARDRVYATGRIPGKELYADVYRQKPMKIIQKVFVPV 92
            :|:|.:|..|:..|...|.....|:||  .:.:.....:..|::.|.|:...|.:|:.::|.:||
Frog     4 EKYLPELMAEKDSLDPSFVHAMRLLDEEIVKFQDSEGNKEDGEKKYLDIISNKNIKLSERVLIPV 68

  Fly    93 NQYPKFNFAGKILGPKGNSLRRLQEETQCKIALKGRSSMRDRNKEEELR--SDPRYAHLQKNLFL 155
            .|||||||.||:|||:||||:||||||..|:::.|:.||||:.||||||  .:.::|||...|.:
Frog    69 KQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKIKEEELRKSDEAKHAHLSDELHV 133

  Fly   156 EVSTVAIPAECHSRIAYALAEIRKYLIPDNNDEVSHEQLRELMEI----DPESAKNFKGLNLEAY 216
            .:...|.|.|.:||:::||.||:|:|:||.|||:..||||||..:    |.|..|..:|..:
Frog   134 LLEVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIRQEQLRELSYLNGSDDSERGKGTRGRGI--- 195

  Fly   217 RSVRDSNGASKYINLIKRVAENPSK 241
                             ||...||:
Frog   196 -----------------RVPSTPSR 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4021	NP_611610.2	SF1_like-KH	86..202	CDD:239088	63/121 (52%)
khdrbs2	NP_001072215.1	Qua1	5..57	CDD:374463	12/51 (24%)
		SF1_like-KH	61..180	CDD:239088	63/118 (53%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	178..224		8/46 (17%)
		Sam68-YY	263..317	CDD:374636
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	321..345
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	57	1.000	Domainoid score	I10668
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D428083at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9347
Panther	1	1.100	-	-	O	PTHR11208
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.020