DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4021 and khdrbs2

DIOPT Version :9

Sequence 1:	NP_611610.2	Gene:	CG4021 / 37484	FlyBaseID:	FBgn0034659	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_001070758.1	Gene:	khdrbs2 / 768147	ZFINID:	ZDB-GENE-061013-497	Length:	346	Species:	Danio rerio

Alignment Length:	212	Identity:	87/212 - (41%)
Similarity:	128/212 - (60%)	Gaps:	22/212 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 KFLADLDEERQRLSAEFPLCALLIDEARDRVYATGRIPGKEL--------YADVYRQKPMKIIQK 87
            |:|.:|..|::.|.|.|.....|:.|..:      :..|.||        |.|:...|.:|:.::
Zfish     5 KYLPELVAEKESLDASFVHAMRLLAEEIE------KFEGDELRKDGEVKKYLDIISNKNIKLSER 63

  Fly    88 VFVPVNQYPKFNFAGKILGPKGNSLRRLQEETQCKIALKGRSSMRDRNKEEELR--SDPRYAHLQ 150
            |.:||.|||||||.||:|||:|||::||||||..|:::.|:.||||:.||||||  .:.:||||.
Zfish    64 VLIPVQQYPKFNFVGKLLGPRGNSMKRLQEETGAKMSILGKGSMRDKGKEEELRKSGEAKYAHLS 128

  Fly   151 KNLFLEVSTVAIPAECHSRIAYALAEIRKYLIPDNNDEVSHEQLRELMEI----DPESAKNF--K 209
            .:|.:.:...|.|.|.:||:::||.||:|:|:||.|||:..||||||..:    ||...::.  :
Zfish   129 NDLHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIRQEQLRELSYLNGSDDPSRGRSARGR 193

  Fly   210 GLNLEAYRSVRDSNGAS 226
            ||.|.:..|.|....|:
Zfish   194 GLRLTSTASPRGRGSAA 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4021	NP_611610.2	SF1_like-KH	86..202	CDD:239088	63/121 (52%)
khdrbs2	NP_001070758.1	Qua1	6..57	CDD:292891	13/56 (23%)
		SF1_like-KH	61..180	CDD:239088	63/118 (53%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	175..292		9/36 (25%)
		Sam68-YY	<281..>306	CDD:293176
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590100
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5176
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D428083at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm26159
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11208
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.810