DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4021 and Sf1

DIOPT Version :9

Sequence 1:	NP_611610.2	Gene:	CG4021 / 37484	FlyBaseID:	FBgn0034659	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_001104261.1	Gene:	Sf1 / 22668	MGIID:	1095403	Length:	639	Species:	Mus musculus

Alignment Length:	211	Identity:	50/211 - (23%)
Similarity:	94/211 - (44%)	Gaps:	48/211 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EKMENPSEI--TEEQPTTTHEYQPRLNEIAQKFLADLDEERQRLSAEFPLCALLIDEARDRVYAT 64
            ::..:|..|  :|.:...|.|::.|         ..|:|||..|..|  :.||
Mouse    78 DRSPSPEPIYNSEGKRLNTREFRTR---------KKLEEERHTLITE--MVAL------------ 119

  Fly    65 GRIPGKELYADVYRQKPMKIIQKVFVPVNQYPKFNFAGKILGPKGNSLRRLQEETQCKIALKGRS 129
              .|..:..|| |:....::..||.:|.::||:.||.|.::||:||:|:.:::|...||.::|:.
Mouse   120 --NPDFKPPAD-YKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKG 181

  Fly   130 SMRD----RNKEEELRSDPRYAHLQKNLFLEVSTVAIPAECHSRIAYALAEIRKYL-----IPDN 185
            |:::    |...:.|..:....|           ..:.|.....:..|:.:||..|     .|::
Mouse   182 SVKEGKVGRKDGQMLPGEDEPLH-----------ALVTANTMENVKKAVEQIRNILKQGIETPED 235

  Fly   186 NDEVSHEQLRELMEID 201
            .:::...|||||..::
Mouse   236 QNDLRKMQLRELARLN 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4021	NP_611610.2	SF1_like-KH	86..202	CDD:239088	32/125 (26%)
Sf1	NP_001104261.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..44
		Nuclear localization signal. /evidence=ECO:0000255	15..19
		MSL5	17..257	CDD:227503	50/211 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	65..94		3/15 (20%)
		ZnF_C2HC	278..293	CDD:197667
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	325..584
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5176
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810