DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4021 and KHDRBS2

DIOPT Version :9

Sequence 1:	NP_611610.2	Gene:	CG4021 / 37484	FlyBaseID:	FBgn0034659	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	XP_016865823.1	Gene:	KHDRBS2 / 202559	HGNCID:	18114	Length:	413	Species:	Homo sapiens

Alignment Length:	172	Identity:	79/172 - (45%)
Similarity:	115/172 - (66%)	Gaps:	4/172 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 QKFLADLDEERQRLSAEFPLCALLIDEARDRVYAT-GRIPGKE-LYADVYRQKPMKIIQKVFVPV 92
            :|:|.:|..|:..|...|...:.|:.|..::...: |:...:| .|.||...|.:|:.::|.:||
Human     4 EKYLPELMAEKDSLDPSFVHASRLLAEEIEKFQGSDGKKEDEEKKYLDVISNKNIKLSERVLIPV 68

  Fly    93 NQYPKFNFAGKILGPKGNSLRRLQEETQCKIALKGRSSMRDRNKEEELR--SDPRYAHLQKNLFL 155
            .|||||||.||:|||:||||:||||||..|:::.|:.||||:.||||||  .:.:||||...|.:
Human    69 KQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKEEELRKSGEAKYAHLSDELHV 133

  Fly   156 EVSTVAIPAECHSRIAYALAEIRKYLIPDNNDEVSHEQLREL 197
            .:...|.|.|.:||:::||.||:|:|:||.|||:..||||||
Human   134 LIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIRQEQLREL 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4021	NP_611610.2	SF1_like-KH	86..202	CDD:239088	64/114 (56%)
KHDRBS2	XP_016865823.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155056
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5176
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D428083at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8456
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11208
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.810