Protein Alignment LBR and Lbr

DIOPT Version :10

• Sequence 1: NP_726114.1
• Gene: LBR / 37482
• FlyBaseID: FBgn0034657
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_598576.2
• Gene: Lbr / 98386
• MGIID: 2138281
• Length: 626
• Species: Mus musculus
• Alignment Length: 668
• Identity: 164/668 - (24%)
• Similarity: 281/668 - (42%)
• Gaps: 99/668 - (14%)

  Fly   118 GSGSGSSLPIKAAIKARTPIPEVSEV----SSPIRLSTSNL-PMTLTTNTSSG----APNKAFNT 173
            |...||||..:..|.:.....::..|    .:.:.|..|:: |:.......||    :|::...:
Mouse    14 GRWPGSSLYYEVEILSHDNKSQLYTVKYKDGTELELKESDIKPLKSFKQRKSGSISSSPSRRRGS 78

  Fly   174 SSVNSGNSFSRTTTSSTTTTTERIEIRAEGD------GEVDTDSIRKRITERLRRSVSKTISNLA 232
            .|.:...|.||:...:...:...:....|||      .|:..:.::.::|..:.:....::|...
Mouse    79 RSRSRSRSRSRSPGRAPKGSRRSVSASHEGDVKEKKEKEMRREILQVKLTPLVLKPFGNSVSVYN 143

  Fly   233 GTPVTNTEEGSRYSRSVSRSVYDDEKS---SKRSYSTGEEDIDEEDELEEDQFRSFNVTRKSATP 294
            |.|....:..:.|.....|.:...|..   ::.|.....|::..::...|:|    |:..|.  |
Mouse   144 GEPEHMEKNATPYKDKQERIILSTEDRYIVTQYSLRPRREEVKAKEIESEEQ----NLVTKG--P 202

  Fly   295 AEISCRQLKAPR----EFGGWLGAFLFLLLLPTAVYYLTWSCTARNACQFKHLNLGILLDVNYL- 354
            |.:...|:..|:    ||||..||.|.:|.||..|..|...|..::.        |:|.....|
Mouse   203 APLGTFQVTTPQRKDLEFGGVPGAVLIMLGLPACVLLLLLQCRQKDP--------GLLHFPPPLP 259

  Fly   355 -TRQVFQPRVVGAFAAY---QVVVFLL--------VALLPGRRVHLTRETYKFNCLAVSLTLLIA 407
             ..::::|||.|.:..:   |.:..||        ..|:.|||:.     |:.|.|...:....|
Mouse   260 ALHELWEPRVCGVYLLWFFVQALFHLLPVGKVAEGTPLVDGRRLQ-----YRLNGLYAFILTSAA 319

  Fly   408 SGVAEYLKYPVVTFVLRHYLRFCIFGLVGAFVAAAWSYWLVDTAKYNVLRQTLTNDYGRTGSFVV 472
            .|.|.:.... :.::..|:|:..:.....:.:.:|:.|    .......|:.|:.  ..:|:.|.
Mouse   320 LGAAVFWGVE-LCYLYTHFLQLALAATGFSVLLSAYLY----VRSLRAPREELSP--ASSGNAVY 377

  Fly   473 DFALGRQLNPKWLGRVDWKQF-QYRLSLVTTLIYATCYIYQTLVWPQK--PQLGEQEGYLYQAKY 534
            ||.:||:|||: ||..|.|.| :.|..|:..::.....:...:...::  |.|
Mouse   378 DFFIGRELNPR-LGAFDLKFFCELRPGLIGWVVINLVMLLMEMKIQERAAPSL------------ 429

  Fly   535 YWNNVNYDPATLFSASCLLFYVLDAIIFEHHLSSSFELQHEGYGCLLL---LRYAATPYLLTAVT 596
                     |.:...|..|.||:||:..|..|.:|.::.|:|:|.:|.   |.:....|.|.|
Mouse   430 ---------AMILVNSFQLLYVVDALWNEEALLTSMDIMHDGFGFMLAFGDLVWVPFTYSLQA-- 483

  Fly   597 KYFYEQRVPIS-CWYAPLA--VAALLSLGLLVKRFSCAYKYKYRLNSQSPIFANIETIHTYQGSR 658
              ||....|.. .|  |||  :.||...|.::.|.:.:.|..:|.|...|..|:::||||..|..
Mouse   484 --FYLVSHPHDLSW--PLASVIIALKLCGYVIFRCANSQKNAFRKNPTDPKLAHLKTIHTSTGKS 544

  Fly   659 LLLSGMWGWVRQPNYLGDIVALLALAAPMALRPAWPPVLGLSLIILLLLHRATRANARNQARYHS 723
            ||:||.||:||.||||||::..||.:.|....... |...:.....||:||..|...:.:.:|..
Mouse   545 LLVSGWWGFVRHPNYLGDLIMALAWSLPCGFNHLL-PYFYIIYFTALLIHREARDEHQCRRKYGL 608

  Fly   724 SWQRYSTQVRSYILPRVY 741
            :|::|..:|...|.|.:|
Mouse   609 AWEKYCQRVPYRIFPYIY 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LBR	NP_726114.1	ICMT	304..741	CDD:473892	126/462 (27%)
Lbr	NP_598576.2	LBR_tudor	1..55	CDD:462808	9/40 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	52..117		12/64 (19%)
		ICMT	216..626	CDD:473892	125/458 (27%)