Protein Alignment LBR and Lbr

DIOPT Version :10

• Sequence 1: NP_726114.1
• Gene: LBR / 37482
• FlyBaseID: FBgn0034657
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_001380594.1
• Gene: Lbr / 89789
• RGDID: 620813
• Length: 621
• Species: Rattus norvegicus
• Alignment Length: 668
• Identity: 174/668 - (26%)
• Similarity: 283/668 - (42%)
• Gaps: 104/668 - (15%)

  Fly   118 GSGSGSSLPIKAAIKARTPIPEVSEV----SSPIRLSTSNL-PMTLTTNTSSGAPNKAFNTSSVN 177
            |...||||..:..|.:.....:|..|    .:.:.|..|:: |:.......||:.:.:.:....:
  Rat    14 GRWPGSSLYYEVEILSHDNKSQVYTVKYKDGTELELKESDIKPLKSFKQRKSGSTSSSPSRRRSS 78

  Fly   178 SGNSFSRTTTSSTTTTTERIEIRAEGDGEVDTDSIRKRITE-RLRRSVSKTISN----------- 230
            ...|.||:.:........|..:.|....:.....:|:.|.: :|...|.|..:|
  Rat    79 RSRSRSRSRSPGRAPKGSRRSVSASYQADAKEKEMRREILQVKLTPLVLKPFANSVSVYNGEPEH 143

  Fly   231 --LAGTPVTNTEEGSRYSRSVSRSVYDDEKSSKRSYSTGEEDIDEED-ELEEDQFRSFNVTRKSA 292
              .:.||..|.:|      .|..|..|...:::.|.....|::..:: |.||...    |||
  Rat   144 MEKSATPPKNKQE------RVILSTEDSYIATQYSLRPRREEVKTKNIESEEQNL----VTR--- 195

  Fly   293 TPAEISCRQLKAPR----EFGGWLGAFLFLLLLPTAVYYLTWSCTARNACQFKHLNLGILLDVNY 353
            .|..:...|:..|:    ||||..||.|.:|.||..|:.|...|..::.        |:|.....
  Rat   196 GPVPLGTFQVTTPQRRDLEFGGVPGALLIMLGLPACVFLLLLQCAQKDP--------GLLQFPPP 252

  Fly   354 L--TRQVFQPRVVGAFAAYQVVVFL--LVALLP-GRRVHLT------RETYKFNCLAVSLTLLIA 407
            |  .|::::.||.|   .|.:..||  |.:||| |:.|..|      |..|:.|.|...:....|
  Rat   253 LPALRELWEARVCG---VYLLWFFLQALFSLLPVGKVVEGTPLVDGRRLKYRLNGLYAFILTSAA 314

  Fly   408 SGVAEYLKYPVVTFVLRHYLRFCIFGLVGAFVAAAWSYWLVDTAKYNVLRQTLTNDYGRTGSFVV 472
            .|.|.:....:. ::..|:|:|.:..:|.:.|.:.:.|    .....|.|..|:.  ..:|:.|.
  Rat   315 VGTAVFWDIELY-YLYTHFLQFALAAIVFSVVLSVYLY----ARSLKVPRDELSP--ASSGNAVY 372

  Fly   473 DFALGRQLNPKWLGRVDWKQF-QYRLSLVTTLIYATCYIYQTLVWPQK--PQLGEQEGYLYQAKY 534
            ||.:||:|||: :|..|.|.| :.|..|:..::.....:...:...::  |.|.
  Rat   373 DFFIGRELNPR-IGAFDLKFFCELRPGLIGWVVINLVMLLAEMKVQERSAPSLA----------- 425

  Fly   535 YWNNVNYDPATLFSASCLLFYVLDAIIFEHHLSSSFELQHEGYGCLLL---LRYAATPYLLTAVT 596
                     .||.: |..|.||:||:.||..|.::.::.|:|:|.:|.   |.:....|.|.|
  Rat   426 ---------MTLVN-SFQLLYVVDALWFEEALLTTMDIIHDGFGFMLAFGDLVWVPFTYSLQA-- 478

  Fly   597 KYFYEQRVPIS-CWYAPLA--VAALLSLGLLVKRFSCAYKYKYRLNSQSPIFANIETIHTYQGSR 658
              ||....|.. .|  |||  :.||...|.::.|.:.:.|..:|.|...|..|:::||.|..|..
  Rat   479 --FYLVNHPQDLSW--PLASVIIALKLCGYVIFRCANSQKNAFRKNPTDPKLAHLKTIPTSTGKS 539

  Fly   659 LLLSGMWGWVRQPNYLGDIVALLALAAPMALRPAWPPVLGLSLIILLLLHRATRANARNQARYHS 723
            ||:||.||:||.||||||::..||.:.|....... |...:.....||:||..|...:.:.:|..
  Rat   540 LLVSGWWGFVRHPNYLGDLIMALAWSLPCGFNHIL-PYFYVIYFTALLIHREARDEHQCRRKYGL 603

  Fly   724 SWQRYSTQVRSYILPRVY 741
            :|::|..:|...|.|.:|
  Rat   604 AWEKYCQRVPYRIFPYIY 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LBR	NP_726114.1	ICMT	304..741	CDD:473892	132/460 (29%)
Lbr	NP_001380594.1	LBR_tudor	1..55	CDD:462808	10/40 (25%)
		ICMT	213..621	CDD:473892	131/454 (29%)