Protein Alignment LBR and dhcr7

DIOPT Version :10

• Sequence 1: NP_726114.1
• Gene: LBR / 37482
• FlyBaseID: FBgn0034657
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: XP_031755821.1
• Gene: dhcr7 / 394844
• XenbaseID: XB-GENE-920362
• Length: 487
• Species: Xenopus tropicalis
• Alignment Length: 542
• Identity: 122/542 - (22%)
• Similarity: 183/542 - (33%)
• Gaps: 202/542 - (37%)

  Fly   309 GGW----------LGAFLFLL-LLPTAVYYLTWSCTARNACQFKHLNLGILLDVNYLTRQVFQ-- 360
            |.|          |.|.|||| ..|..|||...||.     |::......:||:.:...|:..
 Frog    39 GQWGRAWEVDYFSLAAVLFLLAFAPLIVYYFVMSCD-----QYQCALTAPVLDLYWGKAQLSDIW 98

  Fly   361 ----------PRVVGAFAAYQVVVFLLV-----ALLPGRR------------------------- 385
                      .::...:.::||.:::||     ..:||..
 Frog    99 DKTPALTWGAAKIYIVWVSFQVFLYMLVPDILHKFVPGYEGGVQEGARTPAGLINKYQVNGLQAW 163

  Fly   386 --VHLT--RETYKFNCLAVSLTLLIASGV-----AEYLKYPVVTFVLRHYLRFCIFGLVGAFVAA 441
              .||.  ...|.|:..  |.|::|.:.|     |..|.|.|.||.|   |:...|
 Frog   164 TITHLLWFANAYHFHWF--SPTIIIDNWVPLLWCANLLGYSVATFAL---LKAYFF--------- 214

  Fly   442 AWSYWLVDTAKYNVLRQTLTNDYGRTGSFVVDFALGRQLNP---KWLGRVDWKQ-FQYRLSLVT- 501
                            .|..:|...||:|..|:.:|.:.||   ||.   |:|. |..|..:|.
 Frog   215 ----------------PTNAHDCKFTGNFFYDYMMGIEFNPRIGKWF---DFKLFFNGRPGIVAW 260

  Fly   502 TLIYATCYIYQTLVWPQKPQLGEQEGY---------------LYQAKYYWNNVNYDPATLFSASC 551
            |||        .|.:..|    :||.|               :|...::||
 Frog   261 TLI--------NLSYAAK----QQELYGQVTNSMILVNVLQAIYVVDFFWN-------------- 299

  Fly   552 LLFYVLDAIIFEHHLSSSFELQHEGYG-------CLLLLRYAATPYLLTAVTKYFYEQRVPISCW 609
                       |.....:.::.|:.:|       |:.|      |||.|....|.....|.:|
 Frog   300 -----------ESWYLKTIDICHDHFGWYLGWGDCVWL------PYLYTLQGLYLVYNPVELS-- 345

  Fly   610 YAPLAVAALLSLGLLVKRFSCAYKYKYRL-NSQSPIF--------------ANIETIHTYQG--- 656
             ...||..|| |||:      .| |.:|: |.|..:|              .:||..:|...
 Frog   346 -TATAVGVLL-LGLI------GY-YIFRMTNHQKDLFRRTNGNCKIWGKKPKSIECSYTSADGKR 401

  Fly   657 --SRLLLSGMWGWVRQPNYLGDIVALLALAAPMALRPAWPPVLGLSLIILLLLHRATRANARNQA 719
              |:|::||.||..|..||.||::..||........... |....:.:.:||:||..|...|..:
 Frog   402 HYSKLMISGFWGVARHLNYTGDLMGSLAYCLACGFDHLL-PYFYFTYMTILLVHRCIRDEHRCSS 465

  Fly   720 RYHSSWQRYSTQVRSYILPRVY 741
            :|...|:.|:..|...:||.::
 Frog   466 KYGKDWKLYTDAVPYRLLPGLF 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LBR	NP_726114.1	ICMT	304..741	CDD:473892	122/540 (23%)
dhcr7	XP_031755821.1	ICMT	111..487	CDD:473892	104/463 (22%)