Protein Alignment LBR and lbr

DIOPT Version :9

• Sequence 1: NP_726114.1
• Gene: LBR / 37482
• FlyBaseID: FBgn0034657
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_001002720.1
• Gene: lbr / 368360
• ZFINID: ZDB-GENE-030804-11
• Length: 619
• Species: Danio rerio
• Alignment Length: 660
• Identity: 166/660 - (25%)
• Similarity: 275/660 - (41%)
• Gaps: 124/660 - (18%)

  Fly   122 GSSLPIKAAIKARTPIPEVSEVSSPIRLSTSNLPMTLTTNTSSGAPNKAFNTSSVNSGNSFSRTT 186
            |:.|.:|.           |:::|.:...|:.     .:.:.|.:|.::...||..|.....|:.
Zfish    44 GTELELKE-----------SDITSVVIFQTAG-----RSRSRSRSPGRSPGRSSARSPGRPRRSR 92

  Fly   187 TSSTTTTTERIEIRAEGDGEVDTDSIRKRITERLRRSVSKTISNLAGTPVT-NTEEGSRYSRSVS 250
            :.|...|..|...|:.   ||..:.:::.:..||             |||. ..|..|..|:|..
Zfish    93 SRSPARTPRRASSRST---EVRKEKLKEVLEVRL-------------TPVAMKHENNSSNSKSEK 141

  Fly   251 RSVYDDEKSSKRSYSTGEEDIDEEDELE----------EDQFRSFNVTRKSATPAEISCRQLKAP 305
            :.   :..::|.:....||..:.|.|.:          :||.....|..|.|..:| ...|.|||
Zfish   142 KG---ENNTAKAAPVVTEEKTETESENQTGGRYNLRRRKDQGDGKAVELKKAVESE-PLLQTKAP 202

  Fly   306 R-------EFGGWLGAFLFLLLLPTAVYYLTWSCTARNA-CQFKHLNLGILLDVNYLTRQVFQPR 362
            .       ||||.:|....:.|||.||..|...|..::| .|...|.|..|..|  ...|||  .
Zfish   203 AAVKTADLEFGGRVGVLFLMFLLPVAVLVLLILCGQKDASLQSFPLELPALQSV--WDCQVF--G 263

  Fly   363 VVGAFAAYQVVVFLL--------VALLPGRRVHLTRETYKFNCLAVSLTLLIASGVAEYLKYPVV 419
            :|..:..:|.|:.||        :.|..|:.:     .|:.|.....|...:|:|||.|.:.. :
Zfish   264 IVLLWLLFQAVLSLLPVGKLVEGMPLKNGKTL-----KYRINGFYALLLTAVAAGVAVYQEVD-L 322

  Fly   420 TFVLRHYLRFCIFGLVGA-------FVAAAWSYWLVDTAKYNVLRQTLTNDY----GRTGSFVVD 473
            :::..|:|:|....|:.|       |:.:.|:                :.|.    |.:|..:.|
Zfish   323 SYIHAHFLQFYTSALLIATLLSIYLFIRSRWA----------------SKDELAPGGNSGYIIYD 371

  Fly   474 FALGRQLNPKWLGRVDWKQF-QYRLSLVTTLIYATCYIYQTLVWPQKPQLGEQEGYLYQAKYYWN 537
            |.:||:|||: :...|.|.| :.|..|:..::..    :..|:...|.|               |
Zfish   372 FFMGRELNPR-IKSFDIKFFCEMRPGLMGWVLIN----FAMLLAEMKQQ---------------N 416

  Fly   538 NVNYDPATLFSASCLLFYVLDAIIFEHHLSSSFELQHEGYGCLLLL-RYAATPYLLTAVTKYFYE 601
            ..|..||.|......|.:|:|.:..|..|.:..::.::|:|.:|.. ..|..|:..|....|...
Zfish   417 LENPSPAMLLVNIFQLLWVIDGLWHEEKLLTMMDIMYDGFGFMLTFGDLAFVPFTFTCQAYYLVN 481

  Fly   602 QRVPISCWYAPLAVAALLSLGLLVKRFSCAYKYKYRLNSQSPIFANIETIHTYQGSRLLLSGMWG 666
            ....:|.::. :.:.|:..:|..:.|.:.:.|:.:|.|...|..::::||.|..|..|::||:||
Zfish   482 HPNELSVFWI-ITLIAMNGVGYYIFRKANSQKFAFRKNPSDPAVSHLKTIPTATGKSLIVSGLWG 545

  Fly   667 WVRQPNYLGDIVALLALAAPMALRPAWPPVLGLSLIILLLLHRATRANARNQARYHSSWQRYSTQ 731
            :||.|||||||:..||.:.|...... .|...|..::.||:||..|...:.:.:|.|:|:.|...
Zfish   546 FVRHPNYLGDIIMALAWSLPCGFNNL-VPYFYLIYLVTLLVHRNARDERQCRKKYGSAWEEYCKA 609

  Fly   732 VRSYILPRVY 741
            |...|.||||
Zfish   610 VPYRIFPRVY 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LBR	NP_726114.1	PEMT	304..741	CDD:304400	124/465 (27%)
lbr	NP_001002720.1	LBR_tudor	1..55	CDD:286541	4/21 (19%)
		PEMT	206..619	CDD:304400	122/460 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	96	1.000	Domainoid score	I7256
eggNOG	1	0.900	-	-		E1_KOG1435
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2455
Inparanoid	1	1.050	141	1.000	Inparanoid score	I4464
OMA	1	1.010	-	-		QHG53801
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000851
OrthoInspector	1	1.000	-	-		oto39314
orthoMCL	1	0.900	-	-		OOG6_102075
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X598
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.730