Protein Alignment LBR and Tm7sf2

DIOPT Version :9

• Sequence 1: NP_726114.1
• Gene: LBR / 37482
• FlyBaseID: FBgn0034657
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_001013089.1
• Gene: Tm7sf2 / 293688
• RGDID: 1311205
• Length: 418
• Species: Rattus norvegicus
• Alignment Length: 457
• Identity: 131/457 - (28%)
• Similarity: 204/457 - (44%)
• Gaps: 64/457 - (14%)

  Fly   303 KAPREFGGWLGAFLFLLLLPTAVYYLTWSCTARNACQFKHLNLGILLDVNYL--TRQVFQPR--- 362
            :||.||||.||....|:|||..:::|..:..:..|        .:|....||  ..:::.||
  Rat     8 QAPLEFGGPLGVTAMLILLPATMFHLLLAARSGPA--------RLLALPAYLPGLEELWSPRALL 64

  Fly   363 VVGAFAAYQVVVFLLVALLPGRRV-------HLTRETYKFNCL-AVSLT-LLIASGVAEYLKYPV 418
            ::..:...||.::    |||.|:|       ..:|..|..|.. |:.|| ||:..||:..|....
  Rat    65 LLFIWLGLQVALY----LLPARKVAEGLELKDKSRLRYPINGFQALVLTALLVGLGVSVGLPLGA 125

  Fly   419 VTFVLRHYLRFCIFGLVGAFVAAAWSYWLVDTAKYNVLRQTLTNDYGRTGSFVVDFALGRQLNPK 483
            :..:|        ..|..|....::.:.|:..||..|...:.....|.:|:.|.||.|||:|||:
  Rat   126 LPGML--------LPLAFATTLTSFIFSLLLYAKALVAPASALAPGGNSGNSVYDFFLGRELNPR 182

  Fly   484 WLGRVDWKQF-QYRLSLVTTLIYATCYIYQTLVWPQKPQLGEQEGYLYQAKYYWNNVNYDPATLF 547
             ||..|:|.| :.|..|:..:......:.|.......|.|         |.:..|...
  Rat   183 -LGSFDFKYFCELRPGLIGWVFINLALLMQEAELRGSPSL---------AMWLVNGFQ------- 230

  Fly   548 SASCLLFYVLDAIIFEHHLSSSFELQHEGYGCLLL---LRYAATPYLLTAVTKYFYEQRVPISCW 609
                 |.||.||:.:|..:.::.::.|:|:|.:|:   |.:....|.|.|....::.|  |:...
  Rat   231 -----LLYVGDALWYEESVLTTMDIIHDGFGFMLVFGDLAWVPFTYSLQAQFLLYHPQ--PLGLP 288

  Fly   610 YAPLAVAALLSLGLLVKRFSCAYKYKYRLNSQSPIFANIETIHTYQGSRLLLSGMWGWVRQPNYL 674
            .| |.:..:.::|..:.|.:.:.|..:|.|...|..|.:|||.|..|.:||:||.||.||.||||
  Rat   289 MA-LLICLIKAVGYYIFRGANSQKNTFRKNPSDPSVAGLETIPTATGRQLLVSGWWGMVRHPNYL 352

  Fly   675 GDIVALLALAAPMALRPAWPPVLGLSLIILLLLHRATRANARNQARYHSSWQRYSTQVRSYILPR 739
            ||::..||.:.|..|.... |...|.....||:||..|...:...:|..:||.|..:|...|:|.
  Rat   353 GDLIMALAWSLPCGLSHLL-PYFYLLYFTALLVHREARDEQQCLRKYGRAWQEYCKRVPYRIIPY 416

  Fly   740 VY 741
            ||
  Rat   417 VY 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LBR	NP_726114.1	PEMT	304..741	CDD:304400	129/454 (28%)
Tm7sf2	NP_001013089.1	PEMT	8..418	CDD:419701	129/455 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	99	1.000	Domainoid score	I6883
eggNOG	1	0.900	-	-		E1_KOG1435
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	132	1.000	Inparanoid score	I4518
OMA	1	1.010	-	-		QHG53801
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000851
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102075
Panther	1	1.100	-	-	LDO	PTHR21257
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X598
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.830