Protein Alignment LBR and dhcr-7

DIOPT Version :10

• Sequence 1: NP_726114.1
• Gene: LBR / 37482
• FlyBaseID: FBgn0034657
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_507941.2
• Gene: dhcr-7 / 181886
• WormBaseID: WBGene00007126
• Length: 457
• Species: Caenorhabditis elegans
• Alignment Length: 570
• Identity: 115/570 - (20%)
• Similarity: 201/570 - (35%)
• Gaps: 182/570 - (31%)

  Fly   240 EEGSRYSRSVSRSVYDDEKSSKRSYSTGEEDIDE-EDELEEDQFRSFNVTRKSATPAEISCRQLK 303
            :|.:|..||   |:.....|..|..|..::||.. ::.|::.|              ::|.:.:.
 Worm     2 KELNRIRRS---SLGGSTSSLTRRSSISQKDIQALQETLQKQQ--------------KVSAQMVL 49

  Fly   304 APREFGGWLGAFLFLLLLPTAVYYLTWSCTARNACQFKHLNLGILLDVNYLTRQVFQPRVVGAFA 368
            |            .|:::|.|.::|.:|.:         ::.|:           |.|.:...|.
 Worm    50 A------------LLIIVPPATFFLFYSIS---------IHTGL-----------FVPTITALFL 82

  Fly   369 AYQVV------------------------VFLLV-----ALLPGRRVHLTRETYK-FNCLAVSLT 403
            .:.:|                        :|..|     ||:........||... |:|:...|.
 Worm    83 RFPLVLQCVPPVWDTVAWKFSAVHCAIQLIFYWVLPHDQALVMSSAGDQMREVNSFFSCILTCLL 147

  Fly   404 LLIASGVAEYLKYPVVTFVLRHYLRF----CIFGLVGAFVAAAWSYWLVDTAKYNVLRQTLTNDY 464
            .::.:....|....|       ||.|    .||.:....:.||    |:.|..:..
 Worm   148 YVLGASAGVYRGDLV-------YLHFNSIILIFAIFAVLIWAA----LIATYHFGT--------- 192

  Fly   465 GRTGSFVVDFALGRQLNPKWLGRVDWKQF-QYRLSLVTTLIYATCYIYQTLVWPQKPQLGEQEGY 528
            |.:.:.:.:|..|.:.:||.|. :|.|.| :.|.:.|              :||.         :
 Worm   193 GNSVTTISEFWFGIENHPKILD-IDLKSFIRTRFTFV--------------IWPL---------F 233

  Fly   529 LYQAKYYWNNVNYDPATLFSASCL----LFYVLDAIIFEHHLS-----SSFELQHEGYGCLLL-- 582
            :..|.|: :.:.|...:. |..||    |.|     ||:.|.:     :|.:.:...:|...:
 Worm   234 VISAMYF-HKITYGQIST-SLVCLSSVQLLY-----IFQFHWNEDLFLNSLDSKRCDFGFYRIWA 291

  Fly   583 ------LRYAATPYLLTAVTKYFYEQRVPISCWYAPLAVAALLSLGLLVKRFSC-AYKYKYRLNS 640
                  :.|.:...:|.|..:   ...|..:|.:..:|:      |.:|....| ..||::|.:.
 Worm   292 DFVLGPIIYTSPVTILVATNR---SVGVISNCLFCAVAI------GSMVFTAKCDRQKYEFRKSK 347

  Fly   641 QSP---------IFANIETIHTYQGSRLLL-SGMWGWVRQPNYLGDIVALLALAA----PMALRP 691
            .:.         |.|...|......:.||| ||.||..|.|||..:.:...|.:|    |..:
 Worm   348 GTLKVGGVDAFFISAKYRTDSGDANTNLLLGSGHWGVCRHPNYASEAITFAAFSAFQGFPSTI-- 410

  Fly   692 AWPPVLGLSLIILLLLHRATRANARNQARYHSSWQRYSTQVRSYILPRVY 741
            |..|.|   .:||.|:.||.....|...:|...|.:|.::|:...||.|:
 Worm   411 AHIPSL---FVILFLVARAFTDENRCLIKYGQYWAQYCSKVKYRFLPGVF 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LBR	NP_726114.1	ICMT	304..741	CDD:473892	101/503 (20%)
dhcr-7	NP_507941.2	ICMT	81..457	CDD:473892	92/440 (21%)