Protein Alignment HmgZ and SOX9

DIOPT Version :10

• Sequence 1: NP_726106.1
• Gene: HmgZ / 37480
• FlyBaseID: FBgn0010228
• Length: 111
• Species: Drosophila melanogaster
• Sequence 2: NP_000337.1
• Gene: SOX9 / 6662
• HGNCID: 11204
• Length: 509
• Species: Homo sapiens
• Alignment Length: 112
• Identity: 28/112 - (25%)
• Similarity: 54/112 - (48%)
• Gaps: 20/112 - (17%)

  Fly     2 SGDRP--KRPLSAYMLWLNETREQIKKDNPGSKVTDIAKRGGELWRGL--KDKTEWEQKAIKMKE 62
            |.::|  |||::|:|:|....|.::....|.....:::|..|:|||.|  .:|..:.::|.:::.
Human    99 SKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRV 163

  Fly    63 EYNKAVKEYEANGGTDSGAPKKRKKAAAKPAKKAKKKESSEEEEEDE 109
            ::.|...:|:..       |::||..         |...:|.||..|
Human   164 QHKKDHPDYKYQ-------PRRRKSV---------KNGQAEAEEATE 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HmgZ	NP_726106.1	HMG-box_SSRP1-like	8..72	CDD:438810	16/65 (25%)
SOX9	NP_000337.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..67
		Sox_N	22..94	CDD:463586
		Dimerization (DIM). /evidence=ECO:0000305|PubMed:31194875	63..103		1/3 (33%)
		PQA. /evidence=ECO:0000305|PubMed:31194875	63..103		1/3 (33%)
		HMG-box_SoxE	104..178	CDD:438840	19/80 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	160..273		10/51 (20%)
		Transactivation domain (TAM). /evidence=ECO:0000269|PubMed:31194875	224..307
		9aaTAD 1. /evidence=ECO:0000269|PubMed:31194875	275..284
		9aaTAD 2. /evidence=ECO:0000269|PubMed:31194875	290..298
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	330..415
		Transactivation domain (TAC). /evidence=ECO:0000269|PubMed:8640233	394..509
		9aaTAD 3. /evidence=ECO:0000269|PubMed:34342803	460..468
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	479..509