DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HmgZ and UBTFL1

DIOPT Version :9

Sequence 1:	NP_001286694.1	Gene:	HmgZ / 37480	FlyBaseID:	FBgn0010228	Length:	111	Species:	Drosophila melanogaster
Sequence 2:	NP_001137447.1	Gene:	UBTFL1 / 642623	HGNCID:	14533	Length:	393	Species:	Homo sapiens

Alignment Length:	126	Identity:	32/126 - (25%)
Similarity:	52/126 - (41%)	Gaps:	35/126 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DRPKRPLSAYMLWLNETREQIKKDNPGSKVTDIAKRGGELWRGL-------------KDKTEWEQ 55
            |.|||||:||..:..|:..|..:..||.:..::.|...:.:|.|             |:|.|:|:
Human    98 DFPKRPLTAYNRFFKESWPQYSQMYPGMRSQELTKILSKKYRELPEQMKQKYIQDFRKEKQEFEE 162

  Fly    56 KAIKMKEEY-----------------NKAVKEYEANGGTDSGAPK-----KRKKAAAKPAK 94
            |..:.:||:                 ||..|:::.|.......||     |:.|...:|.|
Human   163 KLARFREEHPDLVQKAKKSSVSKRTQNKVQKKFQKNIEEVRSLPKTDRFFKKVKFHGEPQK 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HmgZ	NP_001286694.1	HMG_box	6..71	CDD:395407	24/94 (26%)
UBTFL1	NP_001137447.1	HMGB-UBF_HMG-box	100..165	CDD:238686	19/64 (30%)
		HMGB-UBF_HMG-box	223..285	CDD:238686	1/1 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	308..393
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900