Protein Alignment HmgZ and SOX8

DIOPT Version :10

• Sequence 1: NP_726106.1
• Gene: HmgZ / 37480
• FlyBaseID: FBgn0010228
• Length: 111
• Species: Drosophila melanogaster
• Sequence 2: NP_055402.2
• Gene: SOX8 / 30812
• HGNCID: 11203
• Length: 446
• Species: Homo sapiens
• Alignment Length: 86
• Identity: 23/86 - (26%)
• Similarity: 46/86 - (53%)
• Gaps: 9/86 - (10%)

  Fly     7 KRPLSAYMLWLNETREQIKKDNPGSKVTDIAKRGGELWRGL--KDKTEWEQKAIKMKEEYNKAVK 69
            |||::|:|:|....|.::....|.....:::|..|:|||.|  .:|..:.::|.:::.::.|...
Human   103 KRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHP 167

  Fly    70 EYEANGGTDSGAPKKRKKAAA 90
            :|:..       |::||.|.|
Human   168 DYKYQ-------PRRRKSAKA 181

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HmgZ	NP_726106.1	HMG-box_SSRP1-like	8..72	CDD:438810	16/65 (25%)
SOX8	NP_055402.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..58
		Sox_N	18..89	CDD:463586
		Dimerization (DIM). /evidence=ECO:0000303|PubMed:31194875	58..100
		HMG-box_SoxE	101..175	CDD:438840	19/78 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	155..259		8/34 (24%)
		Transactivation domain (TAM). /evidence=ECO:0000303|PubMed:31194875	224..298
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	318..378
		Transactivation domain (TAC). /evidence=ECO:0000303|PubMed:31194875	335..446
		9aaTAD. /evidence=ECO:0000269|PubMed:34342803	400..408
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	425..446