DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HmgZ and Hmgb2

DIOPT Version :9

Sequence 1:	NP_001286694.1	Gene:	HmgZ / 37480	FlyBaseID:	FBgn0010228	Length:	111	Species:	Drosophila melanogaster
Sequence 2:	NP_058883.1	Gene:	Hmgb2 / 29395	RGDID:	69291	Length:	210	Species:	Rattus norvegicus

Alignment Length:	108	Identity:	47/108 - (43%)
Similarity:	66/108 - (61%)	Gaps:	7/108 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 PKRPLSAYMLWLNETREQIKKDNPGSKVTDIAKRGGELW--RGLKDKTEWEQKAIKMKEEYNKAV 68
            ||||.||:.|:.:|.|.:||.::||..:.|.||:.||:|  :..|||..:||||.|:||:|.|.:
  Rat    95 PKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDI 159

  Fly    69 KEYEANGGTDSGAPKKRKKAAAKPAKKAKKKESSEEEEEDESE 111
            ..|.|.|.::.|     ||...:|....||.|..:||||:|.|
  Rat   160 AAYRAKGKSEVG-----KKGPGRPTGSKKKNEPEDEEEEEEEE 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HmgZ	NP_001286694.1	HMG_box	6..71	CDD:395407	31/66 (47%)
Hmgb2	NP_058883.1	HMG_box_2	6..78	CDD:401091
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	51..102		5/6 (83%)
		HMG_box	95..162	CDD:395407	31/66 (47%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	162..210		16/41 (39%)
		Required for chemotactic activity. /evidence=ECO:0000250\|UniProtKB:P26583	165..180		5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1641977at2759
OrthoFinder	1	1.000	-	-		FOG0000133
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820