DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HmgZ and Tox4

DIOPT Version :9

Sequence 1:	NP_001286694.1	Gene:	HmgZ / 37480	FlyBaseID:	FBgn0010228	Length:	111	Species:	Drosophila melanogaster
Sequence 2:	NP_075923.2	Gene:	Tox4 / 268741	MGIID:	1915389	Length:	619	Species:	Mus musculus

Alignment Length:	114	Identity:	31/114 - (27%)
Similarity:	50/114 - (43%)	Gaps:	15/114 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DRPKRPLSAYMLWLNETREQIKKDNPGSKVTDIAKRGGELWRGL--KDKTEWEQKAIKMKEEYNK 66
            :.|::|:|||.|:..:|:..||..||.:...:::|....:|..|  :.|..:::|....|:||.|
Mouse   221 NEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLK 285

  Fly    67 AVKEYEANGG-------------TDSGAPKKRKKAAAKPAKKAKKKESS 102
            |:..|:.|..             ..|..|......||.||..|.....|
Mouse   286 ALAAYKDNQECQATVETVELDPVPQSQTPSPPPVTAADPASPAPASTES 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HmgZ	NP_001286694.1	HMG_box	6..71	CDD:395407	21/66 (32%)
Tox4	NP_075923.2	NHP6B	140..>306	CDD:227935	23/84 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	155..227		1/5 (20%)
		Nuclear localization signal. /evidence=ECO:0000255	213..218
		HMG-box	223..288	CDD:238037	21/64 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..335		8/29 (28%)
		PHA03160	<464..530	CDD:165431
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810