| Sequence 1: | NP_004968.2 | Gene: | KCNC3 / 3748 | HGNCID: | 6235 | Length: | 757 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001189037.1 | Gene: | Shab / 38352 | FlyBaseID: | FBgn0262593 | Length: | 1607 | Species: | Drosophila melanogaster |
| Alignment Length: | 967 | Identity: | 251/967 - (25%) |
|---|---|---|---|
| Similarity: | 340/967 - (35%) | Gaps: | 359/967 - (37%) |
- Green bases have known domain annotations that are detailed below.
|
Human 43 PAQPGPA-----ASPAGPPAPR---GPGDRRAEPCPGLPAAAMGRHGGGGGDSG----------- 88
Human 89 ----------------------------------------------------------------- 88
Human 89 ------------------------------------KIVINVGGVRHETYRSTLRTLPGTRLAGL 117
Human 118 ---TEPEAAARF--DYDPGADEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGID 177
Human 178 ETDVEACCWMTYRQ-----HRDAEEALDSFEAPDPAGAANAANAAGAHDGGLDDEAGAGGGGLDG 237
Human 238 AGGELKRLCFQDAGGGAGGPPGGAGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILI 302
Human 303 SITTFCLETHEGFIHISNKTVTQASPIPGAPPENITNVEVETEPFLTYVEGVCVVWFTFEFLMRI 367
Human 368 TFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAA---KDVLGFLRVVRFVRILRIFKLTR 429
Human 430 HFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGF 494
Human 495 WWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKK 559
Human 560 N--------------KHI---------------------------PRPPQPGSPNYCKPDPPPPP 583
Human 584 PP--------------------------------------------HPHHGSGG---ISPPPPIT 601
Human 602 PPSMGVTVAGAYPAGPHTHPGLLR-----------------------GGAGGLGIMGLPPLPAPG 643
Human 644 EPCPLAQEEVIEINRADPRPNGDPAAAALAHEDCPAIDQPAMSPEDKSP----ITPGSRGRYSRD 704
Human 705 RA----------------------CFLLT-DYAPSPDGSIRKATGAPPLPPQDWRKP 738 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| KCNC3 | NP_004968.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..87 | 20/51 (39%) | |
| Important for normal N-type inactivation. /evidence=ECO:0000269|PubMed:26997484 | 1..78 | 17/42 (40%) | |||
| Potassium_chann | 1..>18 | CDD:314363 | |||
| BTB_KCNC1_3 | 89..202 | CDD:349721 | 52/122 (43%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 210..232 | 2/21 (10%) | |||
| Ion_trans | 289..550 | CDD:366146 | 114/263 (43%) | ||
| Selectivity filter. /evidence=ECO:0000250 | 503..508 | 3/4 (75%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 556..613 | 14/144 (10%) | |||
| PHA03247 | <637..752 | CDD:223021 | 27/129 (21%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 682..746 | 20/84 (24%) | |||
| Shab | NP_001189037.1 | BTB | 309..416 | CDD:197585 | 50/106 (47%) |
| BTB_2 | 309..408 | CDD:280393 | 47/98 (48%) | ||
| Ion_trans | 501..700 | CDD:278921 | 100/216 (46%) | ||
| Ion_trans_2 | 613..696 | CDD:285168 | 47/91 (52%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG2126 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D818306at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X19 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 5 | 4.820 | |||||