Protein Alignment CngB and Cngb1

DIOPT Version :10

• Sequence 1: NP_611607.2
• Gene: CngB / 37479
• FlyBaseID: FBgn0266346
• Length: 1040
• Species: Drosophila melanogaster
• Sequence 2: NP_113997.2
• Gene: Cngb1 / 83686
• RGDID: 621809
• Length: 1338
• Species: Rattus norvegicus
• Alignment Length: 1043
• Identity: 305/1043 - (29%)
• Similarity: 484/1043 - (46%)
• Gaps: 201/1043 - (19%)

  Fly    18 EPEASASLLKSSPNILENFAYDEFQPIQTNHPLLKRMATTPVAQSGSQSSSSSTSSTRKAEPKFC 82
            |.||...:.:..|.|.|....:..:..:......::.......:...:..........|.|.|
  Rat   346 ESEAMVEMPRELPQIQEEQEEENEEKEEEEEEKEEKEEKEEEEEKEEEEKREEEKKKEKEEEK-- 408

  Fly    83 DTLERHAFMRNVINQQPESTRRYSTPGEKEAQVRRSLEEITKDLKEIEQFVSATEELMQREKEQE 147
              .|:....:....::.|...:....|::|.:.:...||..|:.||.|:    .||..:.|||::
  Rat   409 --KEKEEEEKGEEEEKEEKEEKEEEEGKEEKEEKEEKEEEEKEEKEEEE----KEEKEEEEKEEK 467

  Fly   148 QMMYSNKENKCPSPVKRVTYKINAYKAPPRRHRPGSPRFYHSRLYFRNGKIGCVDSTEHQNNVGA 212
            :.....:|.:
  Rat   468 EEEEEEEEEE------------------------------------------------------- 477

  Fly   213 THALVKHILHHEKPLVSPDSVRRVLEQDSFEMVPLPGAVPEIVPDPIAIQRAEELAAATGQVVLP 277
                     ..|:|:|..||. .|::.|               .|...::||:...|:..::...
  Rat   478 ---------EEEEPIVLLDSC-LVVQAD---------------VDQCQLERAQPETASIQELPEE 517

  Fly   278 KEEEEEEKSSPLHQVESQPDVDEDEQDVQ---------ICYNESPELQNEDRN--------ERT- 324
            :||:||||.....:.|.:.:.:|:|:..:         ....|.||||.||.:        |.|
  Rat   518 EEEKEEEKKEEEEEKEEEEEKEEEEEKEEEGEATNSTVPATKEHPELQVEDTDAEAGPLIPEETI 582

  Fly   325 ---QRTP----------------------------------SINESEIVAVDEPDTEMNSDVDHR 352
               :|.|                                  |..||.:||..:|.|...:|.:.|
  Rat   583 PPPERPPVSPAKSDTLAVPGAATHRKKLPSQDDEAEELKALSPAESPVVAWSDPTTPQEADGEDR 647

  Fly   353 KPSSAGSLDSQGQQFLRDQVRHLVRRFTARANKVKSRIELPPTPSSSSTVSSPSPPPTKSLHPS- 416
            ..|:|    ||....:.|:::.||:.|..|..|||.::   ..|..:|...||.|.|.|....|
  Rat   648 AASTA----SQNSAIINDRLQELVKMFKERTEKVKEKL---IDPDVTSDEESPKPSPAKKAPDSA 705

  Fly   417 PQHKVRLVPAGQSPHRGRLFEADTPRSNVWLCSSLC--------GANNDERTLDP-QGKIYISWL 472
            |..|.....|.:..|               .|..||        ......:::|| ...:||.||
  Rat   706 PAQKPAEAEAAEEEH---------------YCDMLCCKFKRRPWKMYQFPQSIDPLTNLMYILWL 755

  Fly   473 CVVSLSFLYNAWVIPLRASFPFQTKENTNIWLACDFCADIIYLLDVVFFKHRVMYLFEGFWVKNK 537
            ..|.|::.:|.|:||:|.:||:|..:|.::||..|:..|.|||||:..|:.|:.::..|..:.:|
  Rat   756 FFVVLAWNWNCWLIPVRWAFPYQRADNIHLWLLMDYLCDFIYLLDITVFQMRLQFVKGGDIITDK 820

  Fly   538 NLTRKNYMRKLQFKLDLLALLPLELLYFKLGTQAVWLRFPRFFKIQSFWEVFRLLDRVISSPHFV 602
            ...|.||::..:||:|||.||||:.||.|||...: ||.||..|..:|:|....|:.::|..:..
  Rat   821 KEMRNNYLKSQRFKMDLLCLLPLDFLYLKLGVNPL-LRLPRCLKYMAFFEFNNRLEAILSKAYVY 884

  Fly   603 RVAKTLTYMLYMIHITAALYYAYSDYQGLGQNRWVFSGKGHPYVRCFAFATKTATSIGKNPKPER 667
            ||.:|..|:||.:|:.:.|||..|.:||:|...||:.|.|:.|:||:.:|.||..:||..|.|:.
  Rat   885 RVIRTTAYLLYSLHLNSCLYYWASAFQGIGSTHWVYDGVGNSYIRCYYWAVKTLITIGGLPDPQT 949

  Fly   668 QGEYVFMTVAWLMGVFVFALLIGQIRDIISTATRNKHEYRQLEDETLEYMRRLNLSQEVQSRVKM 732
            ..|.||..:.:..|||.|:::|||:||::..||..:..||...|.|::||....:.:.||:|||.
  Rat   950 LFEIVFQLLNYFTGVFAFSVMIGQMRDVVGAATAGQTYYRSCMDSTVKYMNFYKIPRSVQNRVKT 1014

  Fly   733 WFQFTWEQQRTLDESNILDALPINLKTDIAISVHIQTLSKVQLFADCEEALLRDLVLKLRAVTFL 797
            |:::||..|..||||.::..||..::.|:||.|:...:|||.||..|:..::.|::.:||:|.:|
  Rat  1015 WYEYTWHSQGMLDESELMVQLPDKMRLDLAIDVNYNIVSKVALFQGCDRQMIFDMLKRLRSVVYL 1079

  Fly   798 PGDFVCRKGEVGREMYIVKLGQVQVMGGPSSDVVLATLTEGSVFGEISLLGINGADRRTADVRSK 862
            |.|:||:|||:||||||::.|||||:|||....||.||..||||||||||.:.|.:||||:|.:.
  Rat  1080 PNDYVCKKGEIGREMYIIQAGQVQVLGGPDGKAVLVTLKAGSVFGEISLLAVGGGNRRTANVVAH 1144

  Fly   863 GYSNLFVLSKSDLNEVIAYYPTAQAILKKRARQLMRKNAAREREEERERARSALQADVVIGNPKT 927
            |::|||:|.|.||||::.:||.:|.:|:|:||:::|.|  .:.:||:         .|:|..|:.
  Rat  1145 GFTNLFILDKKDLNEILVHYPESQKLLRKKARRMLRNN--NKPKEEK---------SVLILPPRA 1198

  Fly   928 PETAPKLLQTVIQALPFESPAVVLITRGSK-----RMR-RKRQSVQMETIVEPKMEVTGAAETQD 986
              ..|||....:.|.....|      ||:|     .:| |.::...:|.....:..:..|..:|:
  Rat  1199 --GTPKLFNAALAAAGKMGP------RGAKGGKLAHLRARLKELAALEAAARQQQLLEQAKSSQE 1255

  Fly   987 QKG 989
            ..|
  Rat  1256 AGG 1258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CngB	NP_611607.2	PLN03192	411..>891	CDD:215625	198/489 (40%)
		CAP_ED	775..889	CDD:237999	62/113 (55%)
Cngb1	NP_113997.2	PLN03192	743..>1129	CDD:215625	167/386 (43%)
		CAP_ED	1057..1166	CDD:237999	60/108 (56%)