Protein Alignment CngB and cnga3a

DIOPT Version :10

• Sequence 1: NP_611607.2
• Gene: CngB / 37479
• FlyBaseID: FBgn0266346
• Length: 1040
• Species: Drosophila melanogaster
• Sequence 2: XP_005166141.1
• Gene: cnga3a / 567242
• ZFINID: ZDB-GENE-090611-2
• Length: 765
• Species: Danio rerio
• Alignment Length: 801
• Identity: 223/801 - (27%)
• Similarity: 376/801 - (46%)
• Gaps: 156/801 - (19%)

  Fly   212 ATHALVKHILHHEKP------LVSPD----SVRRVLEQDSFEMVPLPGAVPEIVPDPIAIQRAEE 266
            |||.|.:.:   |:|      ...||    |.|....:.|..:...|....:..|.|:|:.....
Zfish    80 ATHRLHREV---ERPDSFLERFRGPDLKDISSRGSNARSSIGLPDRPHKRKKANPWPLAVYNMNN 141

  Fly   267 LAAATGQVVLPKEEEEEEKSSPLHQVESQPDVDEDEQDVQICYNESPELQNEDRNERTQRTPSIN 331
            ......:    ||:::||       ::...|..|:::|      |..|.::|.::|:.
Zfish   142 CNNTDDK----KEDKKEE-------IKKDGDKKEEKKD------EKEEKKDEKKDEKK------- 182

  Fly   332 ESEIVAVDEPDTEMNSDVDHRKPSSAGSLDSQGQQFLRDQVRHLVRRFTARANKVKSRIELPPTP 396
                   ||.|.:.:...|.:|.........:.:...:|.         .:.:|.|.
Zfish   183 -------DEKDEKKDEKKDEKKDEKKDEKKDEKKDDKKDD---------KKDDKKKD-------- 223

  Fly   397 SSSSTVSSPSPPPTKSLHPSPQHKVRLVPAGQSPHRGRLFEADTPRSNVWLCSSLCGANNDERTL 461
                     :|||.|                                .||:             :
Zfish   224 ---------APPPPK--------------------------------EVWI-------------M 234

  Fly   462 DPQGKIYISWLCVVSLSFLYNAWVIPLRASFPFQTKENTNIWLACDFCADIIYLLDVVFFKHRVM 526
            ||....|..||.:::....||..::..||.|.......|.:|:..|:.:|:||.:| .|.:.|..
Zfish   235 DPASDKYYRWLSIIAAPVFYNLMMLVTRACFNELQNTYTILWIVLDYTSDVIYYMD-TFVRSRTG 298

  Fly   527 YLFEGFWVKNKNLTRKNYMRKLQFKLDLLALLPLELLYFKLGTQAVWLRFPRFFKIQSFWEVFRL 591
            :|.:|..||:......||....|||.|:::::|.:|...|:|.....|||.|.||:...:|.|..
Zfish   299 FLEQGLLVKDSKKLINNYRTIPQFKYDMISMIPTDLFMLKVGFNNPELRFNRLFKMARLFEFFDR 363

  Fly   592 LDRVISSPHFVRVAKTLTYMLYMIHITAALYYAYSDYQGLGQNRWVFSGKGHP--------YVRC 648
            .:...:.|:..|::..:.|:|.:||..|.:::|.|...|.|.:.||:....||        |:.|
Zfish   364 TETRTNYPNIFRISNLVLYILVIIHWNACIFFAISKTIGFGTDTWVYPNISHPEYGRLARKYIYC 428

  Fly   649 FAFATKTATSIGKNPKPERQGEYVFMTVAWLMGVFVFALLIGQIRDIISTATRNKHEYRQLEDET 713
            ..::|.|.|:||:.|.|.|..||:|:.:.:|:||.:||.::|.:..:||....::.|::...|..
Zfish   429 LYWSTLTLTTIGETPPPVRDIEYLFVVMDFLIGVLIFATIVGNVGAMISNMNASRAEFQAKIDSI 493

  Fly   714 LEYMRRLNLSQEVQSRVKMWFQFTWEQQRTLDESNILDALPINLKTDIAISVHIQTLSKVQLFAD 778
            .:||:...:|:::::||..||.:.|.:::|.||..:|..||..||.:|||:||:.||.||::|.|
Zfish   494 KQYMQFRKVSKDLEARVIKWFDYLWTEKKTCDEKEVLKNLPDKLKAEIAINVHLDTLKKVRIFQD 558

  Fly   779 CEEALLRDLVLKLRAVTFLPGDFVCRKGEVGREMYIVKLGQVQVMG--GPSSDVVLATLTEGSVF 841
            ||..||.:|||||:...|.|||::|:||::||||||:|.|::.|:.  |.:..||   |::|:.|
Zfish   559 CEAGLLIELVLKLQPQVFSPGDYICKKGDIGREMYIIKEGKLAVVADDGITQFVV---LSDGAYF 620

  Fly   842 GEISLLGINGA---DRRTADVRSKGYSNLFVLSKSDLNEVIAYYPTAQAILKKRARQLMRKN--- 900
            ||||:|||.|:   :||||::||.|||:||.|||.||.|.:..||.|:..|:::.:.::||:
Zfish   621 GEISILGIKGSKAGNRRTANIRSVGYSDLFALSKDDLVEALTEYPDAKKALEEKGKAILRKDNLL 685

  Fly   901 -----AA----REREEERERARSALQADVVIGNPKTPETAPKLLQTVIQALPFESPAVVLITRGS 956
                 ||    ::.||:..|....|  |::.|         |..:.:.:...::......||...
Zfish   686 DEAVAAAGADPKDLEEKIHRLEGNL--DIMTG---------KFAKLMAEYTSYQGKIKQRITNME 739

  Fly   957 KRMRRKRQSVQMETIVEPKME 977
            .:::..|.. .:..::|.|.|
Zfish   740 NKVKTLRPE-DLSEVIEDKKE 759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CngB	NP_611607.2	PLN03192	411..>891	CDD:215625	169/492 (34%)
		CAP_ED	775..889	CDD:237999	61/118 (52%)
cnga3a	XP_005166141.1	Ion_trans	241..483	CDD:459842	75/242 (31%)
		CAP_ED	555..671	CDD:237999	61/118 (52%)
		CLZ	671..740	CDD:465160	14/79 (18%)