Protein Alignment CngB and Cnga2

DIOPT Version :10

• Sequence 1: NP_611607.2
• Gene: CngB / 37479
• FlyBaseID: FBgn0266346
• Length: 1040
• Species: Drosophila melanogaster
• Sequence 2: XP_063135893.1
• Gene: Cnga2 / 25411
• RGDID: 2367
• Length: 664
• Species: Rattus norvegicus
• Alignment Length: 703
• Identity: 209/703 - (29%)
• Similarity: 342/703 - (48%)
• Gaps: 131/703 - (18%)

  Fly   395 TPSSSSTVSSPS------PPPTKSLHPSPQHKVRLVPAG-----------------QSPHRGR-- 434
            |..|:...|||:      |||:...:....|:....|..                 .:|.|||
  Rat     3 TEKSNGVKSSPANNHNHHPPPSIKANGKDDHRAGSRPQSVAADDDTSSELQRLAEMDTPRRGRGG 67

  Fly   435 -----------------LFEADTPRSNVWL-------CSSLCGANNDER---------------- 459
                             .|..:.||.:.:|       ..::.....|::
  Rat    68 FQRIVRLVGVIRDWANKNFREEEPRPDSFLERFRGPELQTVTTHQGDDKGGKDGEGKGTKKKFEL 132

  Fly   460 -TLDPQGKIYISWLCVVSLSFLYNAWVIPLRASFPFQTKENTNIWLACDFCADIIYLLDVVFFKH 523
             .|||.|..|..||.|:::..|||..::..||.|....:....:||..|:.:|.:|:.|:: .:.
  Rat   133 FVLDPAGDWYYRWLFVIAMPVLYNWCLLVARACFSDLQRNYFVVWLVLDYFSDTVYIADLI-IRL 196

  Fly   524 RVMYLFEGFWVKNKNLTRKNYMRKLQFKLDLLALLPLELLYFKLGTQAVWLRFPRFFKIQSFWEV 588
            |..:|.:|..||:....|.||:..||||||:.:::|.:|:||.:|..:..:||.|.......:|.
  Rat   197 RTGFLEQGLLVKDPKKLRDNYIHTLQFKLDVASIIPTDLIYFAVGIHSPEVRFNRLLHFARMFEF 261

  Fly   589 FRLLDRVISSPHFVRVAKTLTYMLYMIHITAALYYAYSDYQGLGQNRWVFSGKGHP--------Y 645
            |...:...|.|:..|::..:.|:|.:||..|.:||..|...|.|.:.||:.....|        |
  Rat   262 FDRTETRTSYPNIFRISNLVLYILVIIHWNACIYYVISKSIGFGVDTWVYPNITDPEYGYLAREY 326

  Fly   646 VRCFAFATKTATSIGKNPKPERQGEYVFMTVAWLMGVFVFALLIGQIRDIISTATRNKHEYRQLE 710
            :.|..::|.|.|:||:.|.|.:..||:|:...:|:||.:||.::|.:..:||.....:.|::...
  Rat   327 IYCLYWSTLTLTTIGETPPPVKDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKI 391

  Fly   711 DETLEYMRRLNLSQEVQSRVKMWFQFTWEQQRTLDESNILDALPINLKTDIAISVHIQTLSKVQL 775
            |....||:...:|::::::|..||.:.|..::|:||..:|..||..|:.:|||:||:.||.||::
  Rat   392 DAVKHYMQFRKVSKDMEAKVIKWFDYLWTNKKTVDEREVLKNLPAKLRAEIAINVHLSTLKKVRI 456

  Fly   776 FADCEEALLRDLVLKLRAVTFLPGDFVCRKGEVGREMYIVKLGQVQVMGGPSSDVV--LATLTEG 838
            |.|||..||.:||||||...|.|||::||||::|:||||:|.|::.|:   :.|.|  .|.|:.|
  Rat   457 FQDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVV---ADDGVTQYALLSAG 518

  Fly   839 SVFGEISLLGINGA---DRRTADVRSKGYSNLFVLSKSDLNEVIAYYPTAQAILKKRARQLMRKN 900
            |.|||||:|.|.|:   :||||::||.|||:||.|||.||.|.:..||.|:.:|::|.|:::.|.
  Rat   519 SCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYPDAKKVLEERGREILMKE 583

  Fly   901 AAREREEERERARSALQADVVIGNPKTPETAPKLLQTVIQALPFESPAVVLITRGSKRMRRKRQS 965
            ...:..|    ..::::.||          ..||.|       .|:....|.||.::.:
  Rat   584 GLLDENE----VAASMEVDV----------QEKLEQ-------LETNMDTLYTRFARLL------ 621

  Fly   966 VQMETIVEPKMEVTGAAETQDQKGLKTGRCSPDLLSSIQQELKSKHKFINLTD 1018
                      .|.|||.:...|:           ::.::.::|..|:...|:|
  Rat   622 ----------AEYTGAQQKLKQR-----------ITVLETKMKQNHEDDYLSD 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CngB	NP_611607.2	PLN03192	411..>891	CDD:215625	179/552 (32%)
		CAP_ED	775..889	CDD:237999	62/118 (53%)
Cnga2	XP_063135893.1	None