Protein Alignment CngB and Cnga1

DIOPT Version :10

• Sequence 1: NP_611607.2
• Gene: CngB / 37479
• FlyBaseID: FBgn0266346
• Length: 1040
• Species: Drosophila melanogaster
• Sequence 2: XP_006503772.1
• Gene: Cnga1 / 12788
• MGIID: 88436
• Length: 699
• Species: Mus musculus
• Alignment Length: 546
• Identity: 191/546 - (34%)
• Similarity: 306/546 - (56%)
• Gaps: 51/546 - (9%)

  Fly   461 LDPQGKIYISWLCVVSLSFLYNAWVIPLRASFPFQTKENTNIWLACDFCADIIYLLDVVFFKHRV 525
            :||.|..|.:||..::|..:||..:|..||.|.....:....||..|:.:|::||.| :|.:.|.
Mouse   165 IDPSGNTYYNWLFCITLPVMYNWTMIIARACFDELQSDYLEYWLIFDYVSDVVYLAD-MFVRTRT 228

  Fly   526 MYLFEGFWVKNKNLTRKNYMRKLQFKLDLLALLPLELLYFKLGTQAVWLRFPRFFKIQSFWEVFR 590
            .||.:|..||::....:.|...||||||:|:::|.:|||.|.|.....:|..|..:|...:|.|:
Mouse   229 GYLEQGLLVKDRMKLIEKYKANLQFKLDVLSVIPTDLLYIKFGWNYPEIRLNRLLRISRMFEFFQ 293

  Fly   591 LLDRVISSPHFVRVAKTLTYMLYMIHITAALYYAYSDYQGLGQNRWVFSGKGHP--------YVR 647
            ..:...:.|:..|::..:.|::.:||..|.:||:.|...|.|.:.||:.....|        ||.
Mouse   294 RTETRTNYPNIFRISNLVMYIVIIIHWNACVYYSISKAIGFGNDTWVYPDVNDPEFGRLARKYVY 358

  Fly   648 CFAFATKTATSIGKNPKPERQGEYVFMTVAWLMGVFVFALLIGQIRDIISTATRNKHEYRQLEDE 712
            ...::|.|.|:||:.|.|....||:|:.|.:|:||.:||.::|.|..:||.....:.|::...|.
Mouse   359 SLYWSTLTLTTIGETPPPVLDSEYIFVVVDFLIGVLIFATIVGNIGSMISNMNAARAEFQSRVDA 423

  Fly   713 TLEYMRRLNLSQEVQSRVKMWFQFTWEQQRTLDESNILDALPINLKTDIAISVHIQTLSKVQLFA 777
            ..:||...|:|::::.||..||.:.|..::|:||..:|..||..|:.:|||:||:.||.||::||
Mouse   424 IKQYMNFRNVSKDMEKRVIKWFDYLWTNKKTVDEREVLRYLPDKLRAEIAINVHLDTLKKVRIFA 488

  Fly   778 DCEEALLRDLVLKLRAVTFLPGDFVCRKGEVGREMYIVKLGQVQVMG--GPSSDVVLATLTEGSV 840
            |||..||.:|||||:...:.|||::|:||::||||||:|.|::.|:.  |.:..||   |::||.
Mouse   489 DCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGITQFVV---LSDGSY 550

  Fly   841 FGEISLLGINGA---DRRTADVRSKGYSNLFVLSKSDLNEVIAYYPTAQAILKKRARQLMRKNAA 902
            |||||:|.|.|:   :||||:::|.|||:||.|||.||.|.:..||.|:.:|:::.||::.|:..
Mouse   551 FGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPDAKTMLEEKGRQILMKDGL 615

  Fly   903 REREEERERARSALQADVVIGN----PK-------TPETAPKLLQTVIQALPFESPAVVLITRGS 956
                           .|:.|.|    ||       ..|.:..||||..        |.:|....|
Mouse   616 ---------------LDINIANMGSDPKDLEEKVTRMEGSVDLLQTRF--------ARILAEYES 657

  Fly   957 KRMRRKRQSVQMETIVEPKMEVTGAA 982
            .:.:.|::..::|..::|.:|...:|
Mouse   658 MQQKLKQRLTKVEKFLKPLIETEFSA 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CngB	NP_611607.2	PLN03192	411..>891	CDD:215625	170/442 (38%)
		CAP_ED	775..889	CDD:237999	60/118 (51%)
Cnga1	XP_006503772.1	Ion_trans	172..414	CDD:459842	79/242 (33%)
		CAP_ED	486..602	CDD:237999	60/118 (51%)
		CLZ	602..671	CDD:465160	18/91 (20%)