DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tbp and tbpl1

DIOPT Version :9

Sequence 1:	NP_523805.1	Gene:	Tbp / 37476	FlyBaseID:	FBgn0003687	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_001004932.1	Gene:	tbpl1 / 448323	XenbaseID:	XB-GENE-488460	Length:	186	Species:	Xenopus tropicalis

Alignment Length:	173	Identity:	69/173 - (39%)
Similarity:	108/173 - (62%)	Gaps:	2/173 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   179 LQNIVSTVNLCCKLDLKKIALHARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEDD 243
            :.|:|......|.|:|:||||...|..|. :....|:|::|:||.||.|:||||::||||.||::
Frog    13 ITNVVCVFRTRCHLNLRKIALEGLNVIYK-REVGKVLMKLRKPRITATIWSSGKIICTGATSEEE 76

  Fly   244 SRLAARKYARIIQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHCNFSSYEPELFPGLIYR 308
            :::.||:.||.:|||||..||.:||:.|::..|.:.|.|||......:...:||||||.|.:.||
Frog    77 AKVGARRLARSLQKLGFQVKFTEFKVVNVLAVCTMPFEIRLAEFTKQNRPHASYEPELHPAVCYR 141

  Fly   309 MVRPRIVLLIFVSGKVVLTGAKVRQEIYDAFDKIFPILKKFKK 351
            :...|..|.||.:|.:.:||..|: .:..|.::|:|.:.:.:|
Frog   142 IKSLRTTLQIFSTGSITVTGPDVK-SVATAIEQIYPFVFESRK 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tbp	NP_523805.1	PLN00062	176..351	CDD:177693	68/171 (40%)
Tbp	NP_523805.1	TBP_eukaryotes	176..349	CDD:239952	68/169 (40%)
tbpl1	NP_001004932.1	TLF	9..180	CDD:239953	68/168 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1219067at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920