Protein Alignment Tbp and Trf2

DIOPT Version :10

• Sequence 1: NP_523805.1
• Gene: Tbp / 37476
• FlyBaseID: FBgn0003687
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_001096905.1
• Gene: Trf2 / 31773
• FlyBaseID: FBgn0261793
• Length: 1715
• Species: Drosophila melanogaster
• Alignment Length: 317
• Identity: 94/317 - (29%)
• Similarity: 155/317 - (48%)
• Gaps: 57/317 - (17%)

  Fly    42 DSLMPAPGSSSVQHQQQQQQSD----ASGGSGLFGHEPSLPLAHKQMQSYQPSASYQQQQQQQQL 102
            |:::.|.||.::.....:.:::    ||.|:||...:..| |..:.|||. .......:::::..
  Fly  1195 DTIVLATGSKNMFLTSSENKANLPTVASNGNGLITAKMDL-LEEEVMQSI-TVIDDDDEEKKEVA 1257

  Fly   103 QSQAPGGGGSTPQSMMQPQTPQSMMAHMMPMSERSVGGSGAGGGGDALSNIHQTMGPSTPMTPAT 167
            :.:......:.|..:.||                            ...|.|:.
  Fly  1258 EDEEESSNNAKPIDLHQP----------------------------IADNEHEL----------- 1283

  Fly   168 PGSADPGIVPQLQNIVSTVNLCCKLDLKKIALHARNAEYNPKRFAAVIMRIREPRTTALIFSSGK 232
                  .||  :.|:|.:.::.|.|.|::|||...|.||. :....|.|::|.|.|||.|:|||:
  Fly  1284 ------DIV--INNVVCSFSVGCHLKLREIALQGSNVEYR-RENGMVTMKLRHPYTTASIWSSGR 1339

  Fly   233 MVCTGAKSEDDSRLAARKYARIIQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHCNFSSY 297
            :.||||.||..:::|||:|||.:.|||||.:||:|:|.|::|:|.:.:.|::......|...:||
  Fly  1340 ITCTGATSESMAKVAARRYARCLGKLGFPTRFLNFRIVNVLGTCSMPWAIKIVNFSERHRENASY 1404

  Fly   298 EPELFPGLIYRM--VRPRIVLLIFVSGKVVLTGAKVRQEIYDAFDKIFPILKKFKKQ 352
            ||||.||:.|:|  ..|:..|.||.:|.|.:|.|.| ..:..|...|:|::..|:||
  Fly  1405 EPELHPGVTYKMRDPDPKATLKIFSTGSVTVTAASV-NHVESAIQHIYPLVFDFRKQ 1460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbp	NP_523805.1	TBP_eukaryotes	176..349	CDD:239952	71/174 (41%)
Trf2	NP_001096905.1	PHA03418	<644..732	CDD:177646
		DUF5401	<891..>1088	CDD:375164
		TLF	1283..1456	CDD:239953	72/193 (37%)