DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tbp and tbp1

DIOPT Version :9

Sequence 1:	NP_523805.1	Gene:	Tbp / 37476	FlyBaseID:	FBgn0003687	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_594566.1	Gene:	tbp1 / 2541582	PomBaseID:	SPAC29E6.08	Length:	231	Species:	Schizosaccharomyces pombe

Alignment Length:	207	Identity:	150/207 - (72%)
Similarity:	171/207 - (82%)	Gaps:	17/207 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   162 PMTP-----ATPGSAD------------PGIVPQLQNIVSTVNLCCKLDLKKIALHARNAEYNPK 209
            |:.|     ||..:||            .||||.|||||:||||.|:||||.|||||||||||||
pombe    24 PVLPNANNEATNETADSGDAEVSKNEGVSGIVPTLQNIVATVNLDCRLDLKTIALHARNAEYNPK 88

  Fly   210 RFAAVIMRIREPRTTALIFSSGKMVCTGAKSEDDSRLAARKYARIIQKLGFPAKFLDFKIQNMVG 274
            ||||||||||||::|||||:|||||..|.||||||:||:||||||||||||.|||.||||||:||
pombe    89 RFAAVIMRIREPKSTALIFASGKMVVLGGKSEDDSKLASRKYARIIQKLGFNAKFTDFKIQNIVG 153

  Fly   275 SCDVKFPIRLEGLVLTHCNFSSYEPELFPGLIYRMVRPRIVLLIFVSGKVVLTGAKVRQEIYDAF 339
            |||||||||||||..:|..|||||||||||||||||:|::|||||||||:||||||||:|||.||
pombe   154 SCDVKFPIRLEGLAYSHGTFSSYEPELFPGLIYRMVKPKVVLLIFVSGKIVLTGAKVREEIYQAF 218

  Fly   340 DKIFPILKKFKK 351
            :.|:|:|.:|:|
pombe   219 EAIYPVLSEFRK 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tbp	NP_523805.1	PLN00062	176..351	CDD:177693	141/174 (81%)
Tbp	NP_523805.1	TBP_eukaryotes	176..349	CDD:239952	140/172 (81%)
tbp1	NP_594566.1	PLN00062	55..230	CDD:177693	141/174 (81%)
tbp1	NP_594566.1	TBP_eukaryotes	55..228	CDD:239952	140/172 (81%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	143	1.000	Domainoid score	I1178
eggNOG	1	0.900	-	-		E1_COG2101
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	293	1.000	Inparanoid score	I623
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001202
OrthoInspector	1	1.000	-	-		oto101151
orthoMCL	1	0.900	-	-		OOG6_100597
Panther	1	1.100	-	-	LDO	PTHR10126
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1482
SonicParanoid	1	1.000	-	-		X1201
TreeFam	1	0.960	-	-
	11	10.940