Protein Alignment Tbp and Tbpl2

DIOPT Version :10

• Sequence 1: NP_523805.1
• Gene: Tbp / 37476
• FlyBaseID: FBgn0003687
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_951014.1
• Gene: Tbpl2 / 227606
• MGIID: 2684058
• Length: 350
• Species: Mus musculus
• Alignment Length: 370
• Identity: 180/370 - (48%)
• Similarity: 223/370 - (60%)
• Gaps: 69/370 - (18%)

  Fly     1 MDQMLSPNFSIPSIGTPL--HQMEADQQIVANPVYHPPAVSQPDSLMPAPGSSSVQHQQQQQQSD 63
            |.|:.||       |.||  |.:.::.:.|.:|  |...|.:..:...:...|.:..:..|:..|
Mouse    30 MSQLFSP-------GVPLDMHSLPSNPETVFHP--HLGGVKKASTDFSSVDLSFLPDELTQENRD 85

  Fly    64 ASGGSGLFGHEPSLPLAHKQMQSYQPSASYQQQQQQQQLQSQAPGGGGSTPQSMM---------- 118
            .:........|.|.....:|.|...|    .:...:..|.|.:    ...|||.:
Mouse    86 QTVTGNKLASEESCRTRDRQSQLQLP----DEHGSELNLNSNS----SPDPQSCLCFDDAHSNQP 142

  Fly   119 QPQTPQS------MMAHMMPMSERSVGGSGAGGGGDALSNIHQTMGPSTPMTPATPGSADPGIVP 177
            .|:||.|      ::|.||||:                               ..||.:  ||||
Mouse   143 SPETPNSNALPVALIASMMPMN-------------------------------PVPGFS--GIVP 174

  Fly   178 QLQNIVSTVNLCCKLDLKKIALHARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSED 242
            ||||:|||.||.|||||:||||:|:|.||||||||||||||||||||||||||||:||||||||:
Mouse   175 QLQNVVSTANLACKLDLRKIALNAKNTEYNPKRFAAVIMRIREPRTTALIFSSGKVVCTGAKSEE 239

  Fly   243 DSRLAARKYARIIQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHCNF-SSYEPELFPGLI 306
            :||||||||||::||||||.:|.:|||||||||||||||||||.|.|||..| ||||||||||||
Mouse   240 ESRLAARKYARVVQKLGFPVRFFNFKIQNMVGSCDVKFPIRLEILALTHRQFSSSYEPELFPGLI 304

  Fly   307 YRMVRPRIVLLIFVSGKVVLTGAKVRQEIYDAFDKIFPILKKFKK 351
            |:||:|::|||||.||||||||||.|.|||:||:.::|||:.|||
Mouse   305 YKMVKPQVVLLIFASGKVVLTGAKERSEIYEAFENMYPILESFKK 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbp	NP_523805.1	TBP_eukaryotes	176..349	CDD:239952	139/173 (80%)
Tbpl2	NP_951014.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	82..150		14/75 (19%)
		TBP_eukaryotes	173..347	CDD:239952	139/173 (80%)