Protein Alignment Tbp and tlf-1

DIOPT Version :9

• Sequence 1: NP_523805.1
• Gene: Tbp / 37476
• FlyBaseID: FBgn0003687
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_001122474.1
• Gene: tlf-1 / 172676
• WormBaseID: WBGene00006577
• Length: 508
• Species: Caenorhabditis elegans
• Alignment Length: 401
• Identity: 97/401 - (24%)
• Similarity: 168/401 - (41%)
• Gaps: 92/401 - (22%)

  Fly     3 QMLSPNFSIP--------SIGTPLHQMEA-------DQQIVANPVYHPPA---VSQPDSLMPAPG 49
            |.:..||..|        ::|..:..::.       .:|.|||.:.....   ::|.........
 Worm    83 QPMQVNFGHPGTIAGRNVAVGVQMRPVQGHNVQQGYQRQQVANQIQQQNRAVFMAQNQQGQQQIS 147

  Fly    50 SSSVQHQQQQQQSDASGGSGLFGHEPSLPLAHKQMQSYQPSASYQQQQQQQQLQSQAPGGGGSTP 114
            .:..||:||||.....               |:|.|.:    ::..||.|..:|.:.|....:..
 Worm   148 YAQAQHRQQQQNQQQH---------------HQQPQHF----NHPSQQNQMIMQHRQPQMHHNQQ 193

  Fly   115 QSMMQPQTPQSMMAH------------------MMPMSERS------------VGGSGAGGGGDA 149
            ..|:|||..:..||.                  .:|:.|.|            |...|.....:
 Worm   194 HQMVQPQMTRHQMAQHHAQQPHPQIYVPRDMNLAVPLREPSPEPIPVKIEVPDVPPEGTSAANE- 257

  Fly   150 LSNIHQTMGPSTPMTPATPGSADPGIVPQLQNIVSTVNLCCKLDLKKIALHARNAEYNPKRFAAV 214
                       .||    |...|..|  |::|:|....|...:||:|:|::..|..|  :|...|
 Worm   258 -----------EPM----PDDGDIDI--QIRNVVCNYTLPLHIDLRKLAMNTHNVTY--EREKGV 303

  Fly   215 IMR-IREPRTTALIFSSGKMVCTGAKSEDDSRLAARKYARIIQKLGFPAK----FLDFKIQNMVG 274
            :|: .|.|.....::||||:...|.:||.|.:.|||..||.:|::....|    ..::::.|::.
 Worm   304 MMKQKRSPGCYIKVYSSGKVYIVGCRSEADCKRAARSIARHVQRVMGKTKERVSIRNYRVNNVLA 368

  Fly   275 SCDVKFPIRLEGLVLTHCNFSSYEPELFPGLIYRMVRPRIVLLIFVSGKVVLTGAKVRQEIYDAF 339
            :|.:.|.|::|.:...:.:.|:|||||..||::|.|.|:..|.|..:|.:.:|||:...::.:..
 Worm   369 TCRLPFGIKIEEVAAKYPSESTYEPELSVGLVWRSVTPKATLRIHTTGSITVTGAQSEADVLEVL 433

  Fly   340 DKIFPILKKFK 350
            .||:||:.:|:
 Worm   434 SKIYPIVLEFR 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbp	NP_523805.1	PLN00062	176..351	CDD:177693	57/180 (32%)
		TBP_eukaryotes	176..349	CDD:239952	56/177 (32%)
tlf-1	NP_001122474.1	Med15	<3..>218	CDD:312941	30/153 (20%)
		KLF1_2_4_N	<183..217	CDD:425360	7/33 (21%)
		TLF	266..442	CDD:239953	57/179 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910