Protein Alignment PIG-M and PIGM

DIOPT Version :9

• Sequence 1: NP_611600.1
• Gene: PIG-M / 37470
• FlyBaseID: FBgn0034649
• Length: 466
• Species: Drosophila melanogaster
• Sequence 2: NP_660150.1
• Gene: PIGM / 93183
• HGNCID: 18858
• Length: 423
• Species: Homo sapiens
• Alignment Length: 440
• Identity: 162/440 - (36%)
• Similarity: 226/440 - (51%)
• Gaps: 67/440 - (15%)

  Fly    29 ISALLRIALICYGQLHDSQSAVPYTDIDYKVVTDGARQVLAGDTPFARHTYRYSPIMAYLQTFNI 93
            ::.|.|:||:.||...|....|.||||||:|.||.||.|..|.:|:.|.||||:|::.:|.|.||
Human    24 VAFLARVALVFYGVFQDRTLHVRYTDIDYQVFTDAARFVTEGRSPYLRATYRYTPLLGWLLTPNI 88

  Fly    94 LLHPAWGKLLYATFDLLIATLIYRLVHMEIKSQYQKTVQHLLSKFNRPRDSDQSLDALDERSHPE 158
            .|...:||.|:.:.|||.|.|:|||               ||.|
Human    89 YLSELFGKFLFISCDLLTAFLLYRL---------------LLLK--------------------- 117

  Fly   159 NLARASAC----FWLYNPLTAVISTRGSGDCFSSFFVILTIYLLLKSEHNVTRSYWLIFGAGLAH 219
            .|.|..||    |||.|||...:|:||:.|...:..|::.:||:.|.         |:..|.:.:
Human   118 GLGRRQACGYCVFWLLNPLPMAVSSRGNADSIVASLVLMVLYLIKKR---------LVACAAVFY 173

  Fly   220 GLVIHLRLYPLLFSLAYYLSL------STRLTQTPLDF---LCQILRP--NKQQLCLISGTLISL 273
            |..:|:::||:.:.|...|.|      ...|.|....|   |.::|:.  |:..|..::...::.
Human   174 GFAVHMKIYPVTYILPITLHLLPDRDNDKSLRQFRYTFQACLYELLKRLCNRAVLLFVAVAGLTF 238

  Fly   274 VAFTWTFYTMYGWEYIYEAYLYHFVRKDPRHNFSLQFLLQYLGSASSVAEPSAILKTLVLAPQFL 338
            .|.::.||..||||::...|.||..|:|.|||||..|.:.||.:.|   :.|..|......||
Human   239 FALSFGFYYEYGWEFLEHTYFYHLTRRDIRHNFSPYFYMLYLTAES---KWSFSLGIAAFLPQ-- 298

  Fly   339 LILYLSLSFGQFRQTLPFCIFAVAFVIVTYNSVVTSQYFIWYLAILPLCLNNFKMLSWRRCFGLL 403
            |||..::||..:|. |.||.|....:.||:|.|.|||||:|||.:|||.:...:| .|:|...||
Human   299 LILLSAVSFAYYRD-LVFCCFLHTSIFVTFNKVCTSQYFLWYLCLLPLVMPLVRM-PWKRAVVLL 361

  Fly   404 FLWLLAQALWLLPAYLLEFHTWNTFYWIGLQGAVFFATNGYILEQLLSHY 453
            .||.:.||:||.|||:|||...|||.:|.|.|..|...|..||.|::|||
Human   362 MLWFIGQAMWLAPAYVLEFQGKNTFLFIWLAGLFFLLINCSILIQIISHY 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-M	NP_611600.1	Mannosyl_trans	177..450	CDD:252941	102/283 (36%)
PIGM	NP_660150.1	Mannosyl_trans	140..408	CDD:252941	102/283 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159684
Domainoid	1	1.000	163	1.000	Domainoid score	I3974
eggNOG	1	0.900	-	-		E1_KOG3893
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6274
Inparanoid	1	1.050	251	1.000	Inparanoid score	I3230
Isobase	1	0.950	-	0	Normalized mean entropy	S1177
OMA	1	1.010	-	-		QHG53871
OrthoDB	1	1.010	-	-		D1003258at2759
OrthoFinder	1	1.000	-	-		FOG0004222
OrthoInspector	1	1.000	-	-		oto91517
orthoMCL	1	0.900	-	-		OOG6_102429
Panther	1	1.100	-	-	LDO	PTHR12886
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R511
SonicParanoid	1	1.000	-	-		X2968
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750