Protein Alignment PIG-M and GPI14

DIOPT Version :9

• Sequence 1: NP_611600.1
• Gene: PIG-M / 37470
• FlyBaseID: FBgn0034649
• Length: 466
• Species: Drosophila melanogaster
• Sequence 2: NP_012547.2
• Gene: GPI14 / 853470
• SGDID: S000003774
• Length: 403
• Species: Saccharomyces cerevisiae
• Alignment Length: 455
• Identity: 140/455 - (30%)
• Similarity: 218/455 - (47%)
• Gaps: 81/455 - (17%)

  Fly    28 LISALLRIALICYGQLHDSQSAVPYTDIDYKVVTDGARQVLAGDTPFARHTYRYSPIMAYLQTFN 92
            ::|.|:|:....:|...|:...|.||||||.|..|.|:.|..|.:|:||.||||:|::::|...|
Yeast    10 VLSFLVRVGFFLFGIYQDANFKVRYTDIDYFVFHDAAKYVYEGKSPYARDTYRYTPLLSWLLVPN 74

  Fly    93 ILLHPAW---GKLLYATFDLLIATLIYRLVHMEIKSQYQKTVQHLLSKFNRPRDSDQSLDALDER 154
            ...  .|   ||:::..|||:...:|.:|::..|..:....::.:
Yeast    75 HYF--GWFHLGKVIFVIFDLVTGLIIMKLLNQAISRKRALILESI-------------------- 117

  Fly   155 SHPENLARASACFWLYNPLTAVISTRGSGDCFSSFFVILTIYLLLKSEHNVTRSYWLIFGAGLAH 219
                         ||.||:...|||||:.:......::.|::.|.||.:.:         ||:.:
Yeast   118 -------------WLLNPMVITISTRGNAESVLCCLIMFTLFFLQKSRYTL---------AGILY 160

  Fly   220 GLVIHLRLYPLLFSL-----AYYLSLSTRLTQTPLDFLCQILRPNKQQLCLISGTLISLVAFTWT 279
            ||.||.::||:::.:     .||    .:..|.|...|..:|.       :...||.:|:...|.
Yeast   161 GLSIHFKIYPIIYCIPIAIFIYY----NKRNQGPRTQLTSLLN-------IGLSTLTTLLGCGWA 214

  Fly   280 FYTMYGWEYIYEAYLYHFVRKDPRHNFSLQFLLQYLGSASSVAEPSAILKTLVLAPQFLLIL--- 341
            .|.:||:|::.:|||||..|.|.|||||:..:|.||.||:. ....:.|......||.||:|
Yeast   215 MYKIYGYEFLDQAYLYHLYRTDHRHNFSVWNMLLYLDSANK-ENGESNLSRYAFVPQLLLVLVTG 278

  Fly   342 ---YLSLSFGQFRQTLPFCIFAVAFVIVTYNSVVTSQYFIWYLAILPLCLNNFKMLSWRRCFGLL 403
               :.:.:|....:.|    |...|..||||.|.|||||:|||..||..|:. ..:.|::  |||
Yeast   279 CLEWWNPTFDNLLRVL----FVQTFAFVTYNKVCTSQYFVWYLIFLPFYLSR-THIGWKK--GLL 336

  Fly   404 F--LWLLAQALWLLPAYLLEFHTWNTFY-WIGLQGAVFFATNGYILEQLLSHYGF-TQFKISYRK 464
            .  ||:..|.:||...|.|||...|.|| .:.:...:||.||.::|.|.::.... ||..:|.:|
Yeast   337 MATLWVGTQGIWLSQGYYLEFEGKNVFYPGLFIASVLFFVTNVWLLGQFITDIKIPTQPTVSNKK 401

  Fly   465  464
            Yeast   402  401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-M	NP_611600.1	Mannosyl_trans	177..450	CDD:252941	96/286 (34%)
GPI14	NP_012547.2	Mannosyl_trans	127..386	CDD:252941	96/286 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346495
Domainoid	1	1.000	146	1.000	Domainoid score	I975
eggNOG	1	0.900	-	-		E1_KOG3893
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6274
Inparanoid	1	1.050	205	1.000	Inparanoid score	I837
Isobase	1	0.950	-	0	Normalized mean entropy	S1177
OMA	1	1.010	-	-		QHG53871
OrthoFinder	1	1.000	-	-		FOG0004222
OrthoInspector	1	1.000	-	-		oto100265
orthoMCL	1	0.900	-	-		OOG6_102429
Panther	1	1.100	-	-	LDO	PTHR12886
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R511
SonicParanoid	1	1.000	-	-		X2968
TreeFam	1	0.960	-	-
	16	15.740