DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PIG-M and PNT1

DIOPT Version :9

Sequence 1:	NP_611600.1	Gene:	PIG-M / 37470	FlyBaseID:	FBgn0034649	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_001190361.1	Gene:	PNT1 / 832274	AraportID:	AT5G22130	Length:	470	Species:	Arabidopsis thaliana

Alignment Length:	493	Identity:	157/493 - (31%)
Similarity:	230/493 - (46%)	Gaps:	112/493 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 YTSFRTHLLISALLRIALICYGQLHDSQSAVPYTDIDYKVVTDGARQVLAGDTPFARHTYRYSPI 84
            :..||:.|:.|.|||:.||.||:..|:...|.|||:||.|.:|.|..:.:|::|:.|.||||||:
plant    15 WMKFRSLLVFSMLLRVFLIVYGEWQDAHMEVRYTDVDYIVFSDAASLMASGESPYKRTTYRYSPL 79

  Fly    85 MAYLQTFNILLHPAWGKLLYA--------------------TFDLLIATLIYRLVHMEIKSQYQK 129
            :|.|.|.|...|.:|||.|::                    ..|||:...|:::
plant    80 LALLLTPNSFFHRSWGKFLFSASASQCVDDLFLCRFGIYFHVSDLLVGWFIHKI----------- 133

  Fly   130 TVQHLLSKFNRPRDSDQSLDALDERSHPENLARASACFWLYNPLTAVISTRGSGD---CFSSFFV 191
                                 |.:|..||.:...|...||:||.|..|.|||:.:   |    .:
plant   134 ---------------------LKQRKVPEKICTYSVMVWLFNPFTFTIGTRGNCEPIVC----AM 173

  Fly   192 ILTIYLLLKSEHNVTRSYWLIFGAGLAHGLVIHLRLYPLLFSLAYYLSLSTRL------------ 244
            ||.|.|.|...:.:..::|        :|||:|.|:||::::|...|.|.|::
plant   174 ILWIILCLMQGNLLQAAFW--------YGLVVHFRVYPIIYALPIILVLDTQVFRSGQKPALLYW 230

  Fly   245 ----TQTPLD------FLCQILRPNKQ-------QLCLISGTLISLVAFTWTFYTMYGWEYIYEA 292
                .:||..      ||..:|...|.       ...||||. :.|.....:|| .||.|:::||
plant   231 NTGQAKTPASNMERKTFLFNLLTTLKSLFSRERIMFALISGG-VFLACNAVSFY-FYGQEFLHEA 293

  Fly   293 YLYHFVRKDPRHNFSLQFLLQYLGSASSVAEPSAILKTLVLAPQFLLILYLSLSFGQFRQTLPFC 357
            .|||..|.|||||||:.|...||......   ||:.|.:...|||.:...|...|.   |.|.||
plant   294 LLYHLTRTDPRHNFSIYFYHIYLHYERQF---SAVEKLISFLPQFTVQFALVFCFS---QDLVFC 352

  Fly   358 IFAVAFVIVTYNSVVTSQYFIWYLAILPLCL--NNFKMLSWRRCFGLL--FLWLLAQALWLLPAY 418
            ||......||:|.|:|:|||:|:..:|||.|  ::.| |.|.   |||  .:|:.||..|||..|
plant   353 IFLQTVAFVTFNKVITAQYFVWFYCLLPLILPWSHMK-LKWE---GLLCIIMWIGAQTHWLLWGY 413

  Fly   419 LLEFHTWNTFYWIGLQGAVFFATNGYILEQLLSHYGFT 456
            :|||...|.|..:.:...:|.|.|.::|.:::..:.|:
plant   414 MLEFKGVNVFLPLWIASLLFLAANTFVLVRIIQRHRFS 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PIG-M	NP_611600.1	Mannosyl_trans	177..450	CDD:252941	103/308 (33%)
PNT1	NP_001190361.1	PLN02841	11..470	CDD:178434	157/493 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	132	1.000	Domainoid score	I1670
eggNOG	1	0.900	-	-		E1_KOG3893
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6274
Inparanoid	1	1.050	228	1.000	Inparanoid score	I1158
OMA	1	1.010	-	-		QHG53871
OrthoDB	1	1.010	-	-		D1003258at2759
OrthoFinder	1	1.000	-	-		FOG0004222
OrthoInspector	1	1.000	-	-		oto3840
orthoMCL	1	0.900	-	-		OOG6_102429
Panther	1	1.100	-	-	LDO	PTHR12886
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2968
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840