DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PIG-M and pigm

DIOPT Version :9

Sequence 1:	NP_611600.1	Gene:	PIG-M / 37470	FlyBaseID:	FBgn0034649	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_956684.1	Gene:	pigm / 393361	ZFINID:	ZDB-GENE-040426-1393	Length:	392	Species:	Danio rerio

Alignment Length:	433	Identity:	160/433 - (36%)
Similarity:	219/433 - (50%)	Gaps:	69/433 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 SALLRIALICYGQLHDSQSAVPYTDIDYKVVTDGARQVLAGDTPFARHTYRYSPIMAYLQTFNIL 94
            :||||:.|:|.|...|....:.|||:||.|.||.||.:..|::|:.|.|:||:|::|.|...|:.
Zfish    12 AALLRLLLLCVGVYQDQTLKLKYTDVDYHVFTDAARFITQGESPYRRSTFRYTPLLALLLVPNVY 76

  Fly    95 LHPAWGKLLYATFDLLIATLIYRLVHMEIKSQYQKTVQHLLSKFNRPRDSDQSLDALDERSHPEN 159
            |...:||||:...|||...|::||:                              .|...||
Zfish    77 LSLLFGKLLFGFCDLLSGLLMFRLL------------------------------VLRGASH--- 108

  Fly   160 LARASAC----FWLYNPLTAVISTRGSGDCFSSFFVILTIYLLLKSEHNVTRSYWLIFGAGLAHG 220
               .|||    .||.|||...:||||:.:...:..|:.|:..|...:|..         |.|..|
Zfish   109 ---GSACVSCGLWLLNPLPMAVSTRGNAESVLAVLVLSTLLCLQLRKHTT---------AALLFG 161

  Fly   221 LVIHLRLYPLLFSLAYYLSLSTRLTQTPL---DFLCQILRPNKQQLCLISGTLISLVAFTWTFYT 282
            |.:|:::||    :.|.|.::..||..|.   ..|.:...|...:...:|..:  .::....||.
Zfish   162 LSVHMKIYP----VTYALPIALALTAAPARGRGVLLRFFSPALLRFAAVSAAV--FLSLGLIFYC 220

  Fly   283 MYGWEYIYEAYLYHFVRKDPRHNFSLQFLLQYLGSASSVAEP--SAILKTLVLAPQFLLILYLSL 345
            .||||::.||||||..|:|.|||||..|.|||:     .||.  |:.|..|:|.||.||:|..|.
Zfish   221 RYGWEFLQEAYLYHLTRRDLRHNFSPFFYLQYV-----CAERCWSSGLLPLLLLPQLLLLLLASA 280

  Fly   346 SFGQFRQTLPFCIFAVAFVIVTYNSVVTSQYFIWYLAILPLCLNNFKMLSWRRCFGLLFLWLLAQ 410
            :|.   ..||||.|....|.|::|.|.|||||:|||.:||:.|...::...|... ||.||||.|
Zfish   281 AFS---SDLPFCCFLHTAVFVSFNRVCTSQYFLWYLCLLPVVLPRLRLRLGRGLL-LLLLWLLLQ 341

  Fly   411 ALWLLPAYLLEFHTWNTFYWIGLQGAVFFATNGYILEQLLSHY 453
            .|||.|||||||..||:|.||.....:|..||.:||.|::.||
Zfish   342 GLWLAPAYLLEFQGWNSFSWIWAASLLFLLTNTFILAQIIQHY 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PIG-M	NP_611600.1	Mannosyl_trans	177..450	CDD:252941	108/277 (39%)
pigm	NP_956684.1	PMT_2	23..385	CDD:304453	154/422 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595900
Domainoid	1	1.000	178	1.000	Domainoid score	I3530
eggNOG	1	0.900	-	-		E1_KOG3893
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6274
Inparanoid	1	1.050	256	1.000	Inparanoid score	I3147
OMA	1	1.010	-	-		QHG53871
OrthoDB	1	1.010	-	-		D1003258at2759
OrthoFinder	1	1.000	-	-		FOG0004222
OrthoInspector	1	1.000	-	-		oto40958
orthoMCL	1	0.900	-	-		OOG6_102429
Panther	1	1.100	-	-	LDO	PTHR12886
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R511
SonicParanoid	1	1.000	-	-		X2968
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800