DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10321 and ZBTB45

DIOPT Version :9

Sequence 1:NP_001261124.1 Gene:CG10321 / 37464 FlyBaseID:FBgn0034643 Length:855 Species:Drosophila melanogaster
Sequence 2:NP_001303907.1 Gene:ZBTB45 / 84878 HGNCID:23715 Length:511 Species:Homo sapiens


Alignment Length:356 Identity:94/356 - (26%)
Similarity:120/356 - (33%) Gaps:106/356 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   437 EDDEMLDD-PDGEEIDQDCEYIGEEQDP---------HLSGDVDDDLEYSIMEPPDGETSVD--- 488
            ||||..|| .|||  |.:....||.|.|         .|:...|...|    |||......|   
Human   209 EDDEESDDETDGE--DGEGGGPGEGQAPPSFPDCAAGFLTAAADSACE----EPPAPTGLADYSG 267

  Fly   489 -----------IDQAFMDSEQSHHQQHQEEMQSISLENAVVEFSQATTTTEALVGPTMTVSSA-- 540
                       .:..|.||..|  ..|.|       :.||.|    ...||..|.|...:|.:  
Human   268 AGRDFLRGAGSAEDVFPDSYVS--TWHDE-------DGAVPE----GCPTETPVQPDCILSGSRP 319

  Fly   541 ----SPTPKRAKRSNH-----------QIPAGVTLEPCDHQPPAAGSTTSSKLAAANSRQLVQTA 590
                :|.|..|....|           ..|:|    |....|||...|...:  ||.|.||.:..
Human   320 PGVKTPGPPVALFPFHLGAPGPPAPPPSAPSG----PAPAPPPAFYPTLQPE--AAPSTQLGEVP 378

  Fly   591 SVIAAAGADDNYEIDANLVTEFIRQHTSPLGS---------GRYICHLCSTEFRQFKGLQNHMHS 646
            :..||                   ..|:|.|:         ..|.|..|...|...|....||..
Human   379 APSAA-------------------PTTAPSGTPARTPGAEPPTYECSHCRKTFSSRKNYTKHMFI 424

  Fly   647 HTNWIRANCKKQPQCQICLKSFKGPGMLRMHMKTHDAESSTPMCTICNRTFKSKAILYRHRQTHQ 711
            |:.      :|..||.:|.:||.....|..||.||....:. .|.:|.:.|..|:.|..|.:||:
Human   425 HSG------EKPHQCAVCWRSFSLRDYLLKHMVTHTGVRAF-QCAVCAKRFTQKSSLNVHMRTHR 482

  Fly   712 -QRAYCCGVANCRKNFSSAVNLKWHVERKHP 741
             :||.|   ..|.|.||....|:.|: ..||
Human   483 PERAPC---PACGKVFSHRALLERHL-AAHP 509

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10321NP_001261124.1 zf-AD 12..80 CDD:214871
ASF1_hist_chap <405..516 CDD:304562 27/102 (26%)
C2H2 Zn finger 627..647 CDD:275368 6/19 (32%)
C2H2 Zn finger 661..681 CDD:275368 7/19 (37%)
C2H2 Zn finger 690..710 CDD:275368 6/19 (32%)
C2H2 Zn finger 717..740 CDD:275368 6/22 (27%)
C2H2 Zn finger 750..767 CDD:275368
ZBTB45NP_001303907.1 BTB 23..122 CDD:279045
BTB 34..124 CDD:197585
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 159..241 14/33 (42%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 294..403 30/144 (21%)
zf-C2H2 403..425 CDD:278523 7/21 (33%)
COG5048 <405..>472 CDD:227381 21/73 (29%)
C2H2 Zn finger 405..425 CDD:275368 6/19 (32%)
zf-H2C2_2 417..441 CDD:290200 8/29 (28%)
C2H2 Zn finger 433..453 CDD:275368 7/19 (37%)
zf-H2C2_2 445..470 CDD:290200 8/25 (32%)
zf-C2H2 459..481 CDD:278523 6/22 (27%)
C2H2 Zn finger 461..481 CDD:275368 6/19 (32%)
zf-H2C2_2 473..497 CDD:290200 10/26 (38%)
C2H2 Zn finger 488..508 CDD:275368 7/23 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24399
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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