DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10321 and bcl6b

DIOPT Version :9

Sequence 1:	NP_001261124.1	Gene:	CG10321 / 37464	FlyBaseID:	FBgn0034643	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	XP_001333002.2	Gene:	bcl6b / 793278	ZFINID:	ZDB-GENE-120907-1	Length:	550	Species:	Danio rerio

Alignment Length:	368	Identity:	74/368 - (20%)
Similarity:	122/368 - (33%)	Gaps:	103/368 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   459 EEQDPHLSGDVDD-----DLEYSIMEPPDGETSVDIDQAFMDSEQSHHQQHQEEMQSISLENAVV 518
            |.:||     :.|     |..::.::|...:|.:...|..:  |.|.........||....|:..
Zfish   183 EAEDP-----IPDRARIPDESFASLDPGTCQTPIPKTQTKL--EDSSPCTPDSPSQSSGQPNSPA 240

  Fly   519 EFSQATTTTEALVGPTMTVSSASPTPKRAKRSNHQIPAGVTLEP-C----------------DHQ 566
            |.|..:.:.:.   ...:.|..:|.||......::.   :.|.| |                :|.
Zfish   241 ESSGCSLSPQL---KKRSESKLTPDPKACNWKKYKY---IVLNPLCATPIKEEGPEEDRHSQNHA 299

  Fly   567 P------PAAGSTTSS----KLAAANSRQLVQ-------------------------TASVIAAA 596
            |      .||..||::    :.|..|.|:::.                         :.|:....
Zfish   300 PFTSDRMEAASKTTNNIWNGEEAGLNDRKILSLPYNTSQQKISFAPRHVVEHTLQPLSLSISGDQ 364

  Fly   597 GADDNYEID----------------ANLVTE--FIRQ---HTSPLGSG--RYICHLCSTEFRQFK 638
            |....|...                .||.|:  :|..   ||.|..||  .|.|::|..:|.:..
Zfish   365 GLCSPYVCSQIANQGHLLGQHPIKFENLSTQLSYIGNQGTHTKPSSSGDKPYRCNICGAQFNRPA 429

  Fly   639 GLQNHMHSHTNWIRANCKKQPQCQICLKSFKGPGMLRMHMKTHDAESSTPMCTICNRTFKSKAIL 703
            .|:.|...|:.      :|..:|..|...|.....||.|:..|..|...| |..|...|:....|
Zfish   430 NLKTHSRIHSG------EKPYRCDTCGARFVQVAHLRAHVLIHTGEKPYP-CNTCGTRFRHLQTL 487

  Fly   704 YRHRQTHQ-QRAYCCGVANCRKNFSSAVNLKWHVERKHPEVVD 745
            ..|.:.|. ::.|.|  ..|..:|.....|:.|:.:||..:.:
Zfish   488 KSHLRIHTGEKPYSC--EKCHLHFRHKSQLRLHLRQKHGAITN 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10321	NP_001261124.1	zf-AD	12..80	CDD:214871
		ASF1_hist_chap	<405..516	CDD:304562	12/61 (20%)
		C2H2 Zn finger	627..647	CDD:275368	5/19 (26%)
		C2H2 Zn finger	661..681	CDD:275368	6/19 (32%)
		C2H2 Zn finger	690..710	CDD:275368	5/19 (26%)
		C2H2 Zn finger	717..740	CDD:275368	5/22 (23%)
		C2H2 Zn finger	750..767	CDD:275368
bcl6b	XP_001333002.2	BTB	35..146	CDD:306997
		Retinal	<150..263	CDD:330657	17/89 (19%)
		COG5048	386..>475	CDD:227381	26/95 (27%)
		C2H2 Zn finger	418..438	CDD:275368	5/19 (26%)
		C2H2 Zn finger	446..466	CDD:275368	6/19 (32%)
		C2H2 Zn finger	474..494	CDD:275368	5/19 (26%)
		zf-H2C2_2	487..511	CDD:316026	7/25 (28%)
		C2H2 Zn finger	502..520	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24399
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100