Protein Alignment CG10321 and ZNF134

DIOPT Version :10

• Sequence 1: NP_001261124.1
• Gene: CG10321 / 37464
• FlyBaseID: FBgn0034643
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_003426.3
• Gene: ZNF134 / 7693
• HGNCID: 12918
• Length: 427
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 72/289 - (24%)
• Similarity: 107/289 - (37%)
• Gaps: 71/289 - (24%)

  Fly   527 TEALVGPTMTVS-----SASPTPKRAKRSNHQIPAGVTLEPCD----------HQPPAAGST--- 573
            :||.:....|||     |..|...:.::.|.|    .||..|.          |:...:|..
Human   111 SEASIVKNCTVSKEPHPSEKPFTCKEEQKNFQ----ATLGGCQQKAIHSKRKTHRSTESGDAFHG 171

  Fly   574 -----TSSKLAAANSRQ--LVQTASVIAAAGADDNYEID---------ANLVTEFIRQHTSPLGS 622
                 ..|:...|.||:  |||...:   ...:..||..         |.|| :..|.||   |.
Human   172 EQMHYKCSECGKAFSRKDTLVQHQRI---HSGEKPYECSECGKAFSRKATLV-QHQRIHT---GE 229

  Fly   623 GRYICHLCSTEFRQFKGLQNHMHSHTNWIRANCKKQP-QCQICLKSFKGPGMLRMHMKTHDAESS 686
            ..|.|..|...|.:...|..|...||.       :.| :|..|.|.|.....|.:|.:.|:  .:
Human   230 RPYECSECGKTFSRKDNLTQHKRIHTG-------EMPYKCNECGKYFSHHSNLIVHQRVHN--GA 285

  Fly   687 TP-MCTICNRTFKSKAILYRHRQTHQ-QRAYCCGVANCRKNFSSAVNLKWHVERKHPEVVDPLFK 749
            .| .|:.|.:.|:.|:.|.:|...|. :..|.|  ::|.|:|.....|..| :|.|.|  ...|:
Human   286 RPYKCSDCGKVFRHKSTLVQHESIHTGENPYDC--SDCGKSFGHKYTLIKH-QRIHTE--SKPFE 345

  Fly   750 CGECGSLYDNVDSLQLHVESTDHSAEVQI 778
            |.|||..:.         .|:|:.|..::
Human   346 CIECGKFFS---------RSSDYIAHQRV 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10321	NP_001261124.1	zf-AD	12..80	CDD:214871
		COG5137	<405..516	CDD:227466
		C2H2 Zn finger	627..647	CDD:275368	5/19 (26%)
		zf-C2H2	660..681	CDD:395048	6/20 (30%)
		C2H2 Zn finger	661..681	CDD:275368	6/19 (32%)
		SUF4-like	688..>745	CDD:411020	18/58 (31%)
		C2H2 Zn finger	690..714	CDD:411020	7/24 (29%)
		C2H2 Zn finger	690..710	CDD:275368	6/19 (32%)
		C2H2 Zn finger	717..740	CDD:411020	7/22 (32%)
		C2H2 Zn finger	717..740	CDD:275368	7/22 (32%)
		C2H2 Zn finger	750..767	CDD:275368	4/16 (25%)
ZNF134	NP_003426.3	C2H2 Zn finger	52..72	CDD:275370
		C2H2 Zn finger	80..98	CDD:275370
		C2H2 Zn finger	178..198	CDD:275368	7/22 (32%)
		COG5048	<202..358	CDD:227381	49/182 (27%)
		C2H2 Zn finger	206..226	CDD:275368	4/20 (20%)
		C2H2 Zn finger	234..254	CDD:275368	5/19 (26%)
		C2H2 Zn finger	262..282	CDD:275368	6/19 (32%)
		C2H2 Zn finger	290..310	CDD:275368	6/19 (32%)
		C2H2 Zn finger	318..338	CDD:275368	7/22 (32%)
		C2H2 Zn finger	346..366	CDD:275368	7/29 (24%)
		C2H2 Zn finger	374..394	CDD:275368
		zf-H2C2_2	386..410	CDD:463886
		C2H2 Zn finger	402..422	CDD:275368