DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10321 and Zfp422

DIOPT Version :9

Sequence 1:	NP_001261124.1	Gene:	CG10321 / 37464	FlyBaseID:	FBgn0034643	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	NP_001289368.1	Gene:	Zfp422 / 67255	MGIID:	1914505	Length:	237	Species:	Mus musculus

Alignment Length:	145	Identity:	43/145 - (29%)
Similarity:	62/145 - (42%)	Gaps:	13/145 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   625 YICHLCSTEFRQFKGLQNHMHSHTNWIRANCKKQPQCQICLKSFKGPGMLRMHMKTHDAESSTPM 689
            |.|..||..|.|...|..|...||.      ||..:|..|.|||.....|..|.:.|..|... .
Mouse    55 YKCAKCSKSFSQSSTLFQHKKIHTG------KKSHKCADCGKSFFQSSNLIQHRRIHTGEKPY-K 112

  Fly   690 CTICNRTFKSKAILYRHRQTHQ-QRAYCCGVANCRKNFSSAVNLKWHVERKHPEVVDPLFKCGEC 753
            |..|...||..:.|.:|::.|. ::.|||.  .|.:.||.:.:|..| :|.|  ..:..::|.||
Mouse   113 CDECGERFKQSSNLIQHQRIHTGEKPYCCD--ECGRCFSQSSHLIQH-QRTH--TGEKPYQCEEC 172

  Fly   754 GSLYDNVDSLQLHVE 768
            ...:.....|:.|::
Mouse   173 DKCFSQSSHLRQHMK 187

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10321	NP_001261124.1	zf-AD	12..80	CDD:214871
		ASF1_hist_chap	<405..516	CDD:304562
		C2H2 Zn finger	627..647	CDD:275368	7/19 (37%)
		C2H2 Zn finger	661..681	CDD:275368	7/19 (37%)
		C2H2 Zn finger	690..710	CDD:275368	6/19 (32%)
		C2H2 Zn finger	717..740	CDD:275368	7/22 (32%)
		C2H2 Zn finger	750..767	CDD:275368	4/16 (25%)
Zfp422	NP_001289368.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..34
		COG5048	<53..195	CDD:227381	43/145 (30%)
		C2H2 Zn finger	57..77	CDD:275368	7/19 (37%)
		C2H2 Zn finger	85..105	CDD:275368	7/19 (37%)
		C2H2 Zn finger	113..133	CDD:275368	6/19 (32%)
		C2H2 Zn finger	141..161	CDD:275368	7/22 (32%)
		C2H2 Zn finger	169..189	CDD:275368	5/19 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	188..219		43/145 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24399
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100